Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1039107 | 0.85 | IDO1 (0.48) | IDO1KDRKDM4EPPARGPPARA | |
| SCHEMBL17069204 | 0.81 | IDO1 (0.56) | IDO1KDRKDM4EPPARGPPARA | |
| SCHEMBL5234992 | 0.81 | PNMT (0.58) | IDO1 | |
| SCHEMBL4438009 | 0.80 | PPARG (0.56) | IDO1KDRKDM4EPPARGPPARA | |
| SCHEMBL11700717 | 0.80 | KDR (0.46) | IDO1KDRKDM4EPPARGPPARA | |
| SCHEMBL9901109 | 0.79 | SLC7A5 (0.53) | IDO1KDRKDM4EPPARGPPARA | |
| SCHEMBL2424748 | 0.79 | IDO1 (0.45) | IDO1KDRKDM4EPPARGPPARA | |
| SCHEMBL11699587 | 0.78 | PNMT (0.64) | IDO1PYCR1 | |
| SCHEMBL11811734 | 0.78 | IDO1 (0.50) | IDO1KDRKDM4EPPARGPPARA | |
| SCHEMBL2908984 | 0.78 | PPARG (0.53) | IDO1KDRKDM4EPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1851232-A2 | DIHYDROIMIDAZOTHIAZOLE DERIVATIVES | Prosidion Limited (GB) | 2007-11-07 | — | — | EP | disclosed |
| WO-2006085118-A2 | DIHYDROIMIDAZOTHIAZOLE DERIVATIVES | PROSIDION LIMITED (GB) | 2006-08-17 | — | — | WO | disclosed |