Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Trichlorfon. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 2/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trichlorfon SCHEMBL6266785 | 1.00 | LMNA (1.00) | LMNACYP2C19L3MBTL1CYP3A4CYP2C9 | |
| Trichlorfon SCHEMBL27946356 | 1.00 | LMNA (1.00) | LMNACYP2C19L3MBTL1CYP3A4CYP2C9 | |
| Trichlorfon SCHEMBL15972 | 1.00 | LMNA (1.00) | LMNACYP2C19L3MBTL1CYP3A4CYP2C9 | |
| Trichlorfon SCHEMBL7032758 | 0.91 | LMNA (0.83) | LMNACYP2C19L3MBTL1CYP3A4CYP2C9 | |
| Trichlorfon SCHEMBL4750566 | 0.91 | LMNA (0.83) | LMNACYP2C19L3MBTL1CYP3A4CYP2C9 | |
| Trichlorfon SCHEMBL8858383 | 0.91 | LMNA (0.83) | LMNACYP2C19L3MBTL1CYP3A4CYP2C9 | |
| Trichlorfon SCHEMBL28074129 | 0.89 | LMNA (0.80) | LMNACYP2C19L3MBTL1CYP3A4CYP2C9 | |
| Trichlorfon SCHEMBL27797686 | 0.89 | LMNA (0.80) | LMNACYP2C19L3MBTL1CYP3A4CYP2C9 | |
| Trichlorfon SCHEMBL10446443 | 0.83 | LMNA (0.69) | LMNACYP2C19CYP2C9 | |
| Biphenyl SCHEMBL10446339 | 0.83 | LMNA (0.69) | LMNACYP2C19L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 7055 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3578542-B1 | COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO | CORTEVA AGRISCIENCE LLC (US) | 2025-11-12 | — | — | EP | claimed |
| EP-3578543-B1 | COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO | CORTEVA AGRISCIENCE LLC (US) | 2025-08-20 | — | — | EP | claimed |
| US-20250204531-A1 | AN AGROCHEMICAL COMPOSITION | UPL LTD (IN) | 2025-06-26 | — | — | US | claimed |
| EP-3578541-B1 | COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY, AND PROCESSES RELATED THERETO | CORTEVA AGRISCIENCE LLC (US) | 2025-05-28 | — | — | EP | claimed |
| CN-119606815-A | Facial skin care composition containing carpopodium styracifolium extract and preparation method thereof | 澳宝化妆品（惠州）有限公司 | 2025-03-14 | — | — | CN | claimed |
| CN-119449903-A | Method and device for generating telemetry data acquisition transmission protocol of Internet of things | 华能澜沧江水电股份有限公司 | 2025-02-14 | — | — | CN | claimed |
| CN-119325876-A | Composite cultivation medium for restoring vaccinium uliginosum community and application thereof | 中国科学院东北地理与农业生态研究所农业技术中心 | 2025-01-21 | — | — | CN | claimed |
| CN-222041480-U | Crystallization-preventing filling machine for trichlorfon liquid | 张佩如 | 2024-11-22 | — | — | CN | claimed |
| CN-118437244-A | Continuous dipterex synthesis process and production device for process | 南通江山农药化工股份有限公司 | 2024-08-06 | — | — | CN | claimed |
| CN-113559786-B | Continuous granulation technological equipment for trichlorfon | 南通江山农药化工股份有限公司 | 2024-07-19 | — | — | CN | claimed |
| WO-2000047044-A1 | LIGHT, EXTRUDED COMPOSITIONS CONTAINING A LIGHT, EXTRUDABLE, CERAMIC CARRIER, METHODS FOR THEIR USE, AND PROCESSES FOR THEIR PREPARATION | AMERICAN CYANAMID COMPANY (US) | 2000-08-17 | — | — | WO | claimed |
| US-6063393-A | RODS OR PINS TO BE PRESSED INTO PLANTS | NIHON BAYER AGROCHEM K.K. (JP) | 2000-05-16 | — | — | US | claimed |
| EP-0977725-A1 | NEW FATTY ACID DERIVATIVES | NORSK HYDRO ASA (NO) | 2000-02-09 | — | — | EP | claimed |
| WO-1998032718-A1 | NEW FATTY ACID DERIVATIVES | NORSK HYDRO ASA (NO) | 1998-07-30 | — | — | WO | claimed |
| CN-1168380-A | Dichlorvos producing technology | QINGHUA ZIGUANG YINGLI CHEMICA (CN) | 1997-12-24 | — | — | CN | claimed |
| WO-1993016373-A1 | APPARATUS FOR OPTICAL INSPECTION OF PATTERNED SUBSTRATES | TENCOR INSTRUMENTS (US) | 1993-08-19 | — | — | WO | claimed |
| CN-2134998-Y | ANTI-POLLUTION DEVICE FOR PREPARATION OF DIPTEREX OR ACETOCHLORAL BY DEALCOLOLIZATION AND DISTILLATION | WEI QINGXIANG (CN) | 1993-06-02 | — | — | CN | claimed |
| CN-1041354-A | MULTI-EFFECT FERTILIZER FOR KILLING INSECTS AND RESISTING WITHERING | ZHANG YUEBO (CN) | 1990-04-18 | — | — | CN | claimed |
| EP-0068297-B1 | A NEW INSECTICIDAL COMPOSITION, PROCESSES FOR ITS PRODUCTION AND ITS USE | A. Nattermann & Cie. GmbH (DE) | 1985-12-18 | — | — | EP | claimed |
| EP-0068297-A1 | A new insecticidal composition, processes for its production and its use | A. Nattermann & Cie. GmbH (DE) | 1983-01-05 | — | — | EP | claimed |