Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Trichlorfon. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 2/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trichlorfon SCHEMBL6266785 | 1.00 | LMNA (1.00) | LMNACYP2C19L3MBTL1CYP3A4CYP2C9 | |
| Trichlorfon SCHEMBL27946356 | 1.00 | LMNA (1.00) | LMNACYP2C19L3MBTL1CYP3A4CYP2C9 | |
| Trichlorfon SCHEMBL116996 | 1.00 | LMNA (1.00) | LMNACYP2C19L3MBTL1CYP3A4CYP2C9 | |
| Trichlorfon SCHEMBL7032758 | 0.91 | LMNA (0.83) | LMNACYP2C19L3MBTL1CYP3A4CYP2C9 | |
| Trichlorfon SCHEMBL4750566 | 0.91 | LMNA (0.83) | LMNACYP2C19L3MBTL1CYP3A4CYP2C9 | |
| Trichlorfon SCHEMBL8858383 | 0.91 | LMNA (0.83) | LMNACYP2C19L3MBTL1CYP3A4CYP2C9 | |
| Trichlorfon SCHEMBL28074129 | 0.89 | LMNA (0.80) | LMNACYP2C19L3MBTL1CYP3A4CYP2C9 | |
| Trichlorfon SCHEMBL27797686 | 0.89 | LMNA (0.80) | LMNACYP2C19L3MBTL1CYP3A4CYP2C9 | |
| Trichlorfon SCHEMBL10446443 | 0.83 | LMNA (0.69) | LMNACYP2C19CYP2C9 | |
| Biphenyl SCHEMBL10446339 | 0.83 | LMNA (0.69) | LMNACYP2C19L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 43065 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026099533-A1 | TREATMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) WITH GPBP1 INHIBITORS | UNIVERSITAT DE VALÈNCIA (ES) | 2026-05-15 | — | — | WO | claimed |
| CN-122016741-A | Method for detecting coumaphos based on carbon quantum dot-ferric ion solution system | 河南医药大学 | 2026-05-12 | — | — | CN | claimed |
| EP-4734762-A1 | BAIT COMPOSITIONS | FMC Corporation (US) | 2026-05-06 | — | — | EP | claimed |
| EP-4723893-A2 | COMPOSITIONS AND METHODS TO MITIGATE PHYTOTOXIC EFFECTS OF AGRICHEMICALS | Ascribe Bioscience Inc. (US) | 2026-04-15 | — | — | EP | claimed |
| EP-4719059-A1 | INCREASED PALATABILITY OF INSECTICIDAL INSECT BAITS | Bio Logic Crop Science, S.L. (ES) | 2026-04-08 | — | — | EP | claimed |
| US-20260083129-A1 | PYRAZOLE AMIDE INSECTICIDES | FMC CORP (US) | 2026-03-26 | — | — | US | claimed |
| US-20260083130-A1 | NOVEL SULFONATE BENZAMIDE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | FMC CORP (US) | 2026-03-26 | — | — | US | claimed |
| EP-4710766-A1 | MIXTURES OF AMBRUTICIN WITH AT LEAST ONE FURTHER PESTICIDE | BASF SE (DE) | 2026-03-18 | — | — | EP | claimed |
| US-12568969-B2 | Pyridine compounds for controlling invertebrate pests | FMC CORPORATION (US) | 2026-03-10 | — | — | US | claimed |
| CN-121577800-A | Non-targeted screening multi-pesticide residue detection method based on high-resolution mass spectrum | 常州市食品药品纤维质量监督检验中心(常州市粮油质量监督检测站、常州纤维检验所) | 2026-02-27 | — | — | CN | claimed |
| EP-0127773-A1 | Pesticidal composition | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-12-12 | — | — | EP | claimed |
| EP-0017738-B1 | AN INSECTICIDAL AND MITICIDAL COMPOSITION WHICH CONTAINS A CARBAMATE AND AN ORGANIC PHOSPHORUS COMPOUND, AND A METHOD OF CONTROLLING INSECTS AND MITES THEREWITH | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-08-08 | — | — | EP | claimed |
| US-4447411-A | Controlling undesired growth of mollusks | UNIVERSITY OF DELAWARE (US) | 1984-05-08 | — | — | US | claimed |
| EP-0068297-A1 | A new insecticidal composition, processes for its production and its use | A. Nattermann & Cie. GmbH (DE) | 1983-01-05 | — | — | EP | claimed |
| EP-0055555-A1 | Substituted ethyl phosphonate, preparation thereof, compositions containing it and use as a systemic insecticide | STAUFFER CHEMICAL COMPANY (US) | 1982-07-07 | — | — | EP | claimed |
| EP-0009215-B1 | ENDOPARASITICIDE PASTES FOR HORSES | BAYER AG (DE) | 1982-01-06 | — | — | EP | claimed |
| US-4277467-A | ANTHELMINTICS, LARVICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-07-07 | — | — | US | claimed |
| EP-0009215-A1 | Endoparasiticide pastes for horses | BAYER AG (DE) | 1980-04-02 | — | — | EP | claimed |
| US-4141975-A | TRICHLORFON DISPERSED IN AN INERT MINERAL OIL | CUTTER LABORATORIES, INC. (US) | 1979-02-27 | — | — | US | claimed |
| US-4093731-A | Methyl-6-n-propoxybenzothiazole-2-carbamate and anthelmintic pharmaceutical compositions thereof | SCHERING CORPORATION (US) | 1978-06-06 | — | — | US | claimed |