Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.36 |
| ▸ | TP53 | P04637 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 5/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | RNF4 | P78317 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | GPX4 | P36969 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11697095 | 0.86 | ALDH1A1 (0.41) | ALDH1A1TP53RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL11701062 | 0.82 | PAX8 (0.44) | ALDH1A1TP53RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL11703111 | 0.80 | ALDH1A1 (0.50) | ALDH1A1TP53RAB9ANPC1PAX8 | |
| SCHEMBL11704132 | 0.79 | ALDH1A1 (0.39) | ALDH1A1TP53RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL11697994 | 0.76 | ALDH1A1 (0.44) | ALDH1A1TP53RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL11702116 | 0.76 | NNMT (0.37) | ALDH1A1TP53RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL11872117 | 0.76 | ALDH1A1 (0.59) | ALDH1A1TP53RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL11699704 | 0.75 | TP53 (0.41) | ALDH1A1TP53RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL11870671 | 0.71 | ALDH1A1 (0.39) | ALDH1A1TP53RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL11866789 | 0.71 | ALDH1A1 (0.39) | ALDH1A1TP53RAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4046554-A | HERBICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1977-09-06 | — | — | US | disclosed |
| US-3966811-A | HERBICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1976-06-29 | — | — | US | disclosed |