Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11704518 | 0.81 | MEN1 (0.42) | ALOX15MEN1KMT2APOLBABL1 | |
| SCHEMBL11621081 | 0.79 | ALOX15 (0.58) | ALOX15MEN1KMT2APOLBABL1 | |
| SCHEMBL15320040 | 0.73 | ALOX15 (0.72) | ALOX15MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL11621616 | 0.71 | ALOX15 (0.51) | ALOX15MEN1KMT2APOLBABL1 | |
| SCHEMBL11616677 | 0.71 | ALOX15 (0.51) | ALOX15KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL11621259 | 0.71 | KMT2A (0.50) | ALOX15MEN1KMT2APOLBABL1 | |
| SCHEMBL11620162 | 0.71 | MEN1 (0.44) | ALOX15MEN1KMT2APOLBABL1 | |
| SCHEMBL11620430 | 0.71 | ALDH1A1 (0.47) | ALOX15MEN1KMT2APOLBABL1 | |
| SCHEMBL11702052 | 0.70 | ALOX15 (0.68) | ALOX15MEN1KMT2APOLBABL1 | |
| SCHEMBL11620639 | 0.70 | ALOX15 (0.53) | ALOX15MEN1KMT2APOLBABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4006246-A | ANTIULCER, SECRETOLYTIC, ANTITUSSIVE, STIMULANT | BOEHRINGER INGELHEIM GMBH (DT) | 1977-02-01 | — | — | US | disclosed |