Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11617446 | 1.00 | ALOX15 (0.53) | ALOX15PTGER4MEN1ABL1POLB | |
| SCHEMBL11620634 | 1.00 | ALOX15 (0.53) | ALOX15PTGER4MEN1ABL1POLB | |
| SCHEMBL11621616 | 0.87 | ALOX15 (0.51) | ALOX15PTGER4MEN1ABL1POLB | |
| SCHEMBL11622267 | 0.85 | ALOX15 (0.47) | ALOX15PTGER4MEN1ABL1POLB | |
| SCHEMBL11622270 | 0.85 | ALOX15 (0.47) | ALOX15PTGER4MEN1ABL1POLB | |
| SCHEMBL11706218 | 0.85 | ALOX15 (0.47) | ALOX15PTGER4MEN1ABL1POLB | |
| SCHEMBL11620181 | 0.83 | LMNA (0.46) | ALOX15PTGER4MEN1ABL1POLB | |
| Hydrochloric Acid SCHEMBL11617273 | 0.83 | SLC2A1 (0.39) | ALOX15MEN1POLBKMT2AMAPT | |
| SCHEMBL11620120 | 0.76 | LMNA (0.45) | ALOX15MAPTLMNACYP1A2CYP3A4 | |
| SCHEMBL11619777 | 0.74 | LMNA (0.51) | ALOX15PTGER4MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE29628-E | ANTIULCER, SECRETOLYTICS, ANTITUSSIVE | BOEHRINGER INGELHEIM GMBH (DT) | 1978-05-09 | — | — | US | disclosed |
| US-4006246-A | ANTIULCER, SECRETOLYTIC, ANTITUSSIVE, STIMULANT | BOEHRINGER INGELHEIM GMBH (DT) | 1977-02-01 | — | — | US | disclosed |
| US-3950393-A | ANTIULCER, ANTISECRETORY, ANTITUSSIVE AGENTS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-04-13 | — | — | US | disclosed |