Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL73391 | 0.88 | KDM4E (0.52) | KDM4EALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL6838077 | 0.86 | ALOX5 (0.51) | KDM4EALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL7948863 | 0.86 | MAOA (0.47) | KDM4EALDH1A1HSD17B10HPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11126128 | 0.83 | MAOA (0.40) | KDM4EALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL10372246 | 0.81 | EDNRA (0.50) | KDM4EALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL11128849 | 0.80 | ALDH1A1 (0.51) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL8509407 | 0.77 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10HPGDNPC1 | |
| SCHEMBL7553333 | 0.76 | AKR1B1 (0.53) | KDM4EALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL4775716 | 0.76 | KDM4E (0.71) | KDM4EALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL6837905 | 0.75 | MAOB (0.53) | KDM4EALDH1A1HSD17B10HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4036982-A | INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-19 | — | — | US | disclosed |