Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6786828 | 0.77 | HTT (0.75) | HTTL3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL28328799 | 0.68 | HTT (1.00) | HTTL3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL9405344 | 0.65 | IDO1 (0.48) | HTTL3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL986968 | 0.62 | HTT (0.59) | HTTL3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL1866693 | 0.61 | HTT (0.65) | HTTL3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL752826 | 0.61 | HTT (0.66) | HTTL3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL24308948 | 0.60 | KMT2A (0.79) | HTTL3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL3807805 | 0.60 | KMT2A (0.73) | HTTL3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL28685764 | 0.60 | KMT2A (0.73) | HTTL3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL29396406 | 0.60 | KMT2A (0.73) | HTTL3MBTL1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064104-A | Phosphine oxide flame retardants | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-12-20 | — | — | US | disclosed |