Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUSP3 | P51452 | 2/20 | 0.50 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17121973 | 0.79 | CYP2C19 (0.52) | DUSP3PTPN5PTPN11CYP2C19CYP2D6 | |
| SCHEMBL2847464 | 0.77 | HSD11B1 (0.49) | DUSP3PTPN5PTPN11CYP2C19CYP2D6 | |
| SCHEMBL9380398 | 0.77 | F2 (0.46) | DUSP3PTPN5PTPN11CYP2C19CYP2D6 | |
| SCHEMBL9805901 | 0.77 | MGLL (0.58) | DUSP3PTPN5PTPN11CYP2C19CYP2D6 | |
| SCHEMBL4421353 | 0.77 | — | — | |
| SCHEMBL154974 | 0.77 | ALDH1A1 (0.65) | DUSP3PTPN5PTPN11CYP2C19CYP2D6 | |
| SCHEMBL13833159 | 0.77 | ALDH1A1 (0.65) | DUSP3PTPN5PTPN11CYP2C19CYP2D6 | |
| SCHEMBL235856 | 0.77 | — | — | |
| SCHEMBL3971866 | 0.77 | ALDH1A1 (0.65) | DUSP3PTPN5PTPN11CYP2C19CYP2D6 | |
| SCHEMBL5997632 | 0.77 | CA12 (0.44) | CYP2C19CYP2D6ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064244-A | ANOREXIGENIC AGENTS, ANTIMIGRAINE AGENTS | SANDOZ LTD. (CH) | 1977-12-20 | — | — | US | disclosed |