Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 6/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL483872 | 0.80 | MIF (0.34) | MIFTAAR1RIPK1KDM4ELMNA | |
| SCHEMBL8763198 | 0.76 | MIF (0.47) | MIFRIPK1TRPA1ALDH1A1CYP3A4 | |
| SCHEMBL8763183 | 0.68 | MIF (0.39) | MIFTAAR1TRPA1ALDH1A1CYP3A4 | |
| SCHEMBL2241061 | 0.68 | MIF (0.39) | MIFTAAR1TRPA1ALDH1A1CYP3A4 | |
| SCHEMBL6889221 | 0.68 | MIF (0.39) | MIFTAAR1TRPA1ALDH1A1CYP3A4 | |
| SCHEMBL4624051 | 0.68 | MIF (0.57) | MIFTAAR1RIPK1TRPA1ALDH1A1 | |
| SCHEMBL5029899 | 0.68 | RIPK1 (0.43) | TAAR1RIPK1LMNAAOC3CACNA1F | |
| SCHEMBL563710 | 0.67 | KDM4E (0.40) | MIFRIPK1TRPA1KDM4ELMNA | |
| SCHEMBL331446 | 0.66 | MIF (0.36) | MIFTRPA1ALDH1A1CYP3A4HPGD | |
| SCHEMBL23880379 | 0.64 | RIPK1 (0.40) | TAAR1RIPK1LMNAAOC3CACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4041208-A | ENERGY ABSORBERS, LAMINATED GLASS SHEETS USEFUL AS AUTOMOBILE WINDSHIELDS | PPG INDUSTRIES, INC. (US) | 1977-08-09 | — | — | US | disclosed |