SCHEMBL483872

SCHEMBL483872

CC(N=C=O)(N=C=O)C(c1ccccc1)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 3/20 0.34
TAAR1 Q96RJ0 2/20 0.33
RIPK1 Q13546 2/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
NR3C1 P04150 1/20 0.32
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32
AOC3 Q16853 1/20 0.32
CACNA1F O60840 1/20 0.32
CHRM2 P08172 1/20 0.32
CHRM1 P11229 1/20 0.32
ADRA2B P18089 1/20 0.32
CHRM3 P20309 1/20 0.32
ADRA1A P35348 1/20 0.32
HRH1 P35367 1/20 0.32
OPRK1 P41145 1/20 0.32
CACNA1D Q01668 1/20 0.32
SLC6A3 Q01959 1/20 0.32
KCNH2 Q12809 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11701075 0.80 MIF (0.47) MIFTAAR1RIPK1KDM4ELMNA
SCHEMBL2298256 0.79 CYP2D6 (0.33) MIFLMNA
SCHEMBL5182817 0.77 MIF (0.34) MIFRIPK1LMNA
SCHEMBL8283160 0.74 MIF (0.37) MIFTAAR1RIPK1CACNA1FCHRM2
SCHEMBL4847089 0.72 RIPK1 (0.36) MIFRIPK1ATML3MBTL1NR3C1
SCHEMBL30265787 0.71 ATM (0.38) MIFTAAR1RIPK1ATML3MBTL1
SCHEMBL10959509 0.71 CYP2C19 (0.30)
SCHEMBL5182810 0.71 CNR1 (0.42) RIPK1KDM4ELMNACACNA1FCHRM2
SCHEMBL7463991 0.69 MIF (0.36) MIFTAAR1RIPK1LMNA
SCHEMBL3018884 0.69 RIPK1 (0.40) RIPK1AOC3CACNA1FCHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2970554-B1 POLYURETHANES, ARTICLES AND COATINGS PREPARED THEREFROM AND METHODS OF MAKING THE SAME PPG IND OHIO INC (US) 2023-09-20 EP claimed
US-11591436-B2 Polyurethane article and methods of making the same PPG INDUSTRIES OHIO, INC. (US) 2023-02-28 US claimed
US-11472912-B2 Polyurethanes, articles and coatings prepared therefrom and methods of making the same PPG INDUSTRIES OHIO, INC. (US) 2022-10-18 US claimed
US-11248083-B2 Aircraft windows PPG INDUSTRIES OHIO, INC. (US) 2022-02-15 US claimed
US-11149107-B2 Polyurethanes, articles and coatings prepared therefrom and methods of making the same PPG INDUSTRIES OHIO, INC. (US) 2021-10-19 US claimed
US-11008418-B2 Polyurethanes, articles and coatings prepared therefrom and methods of making the same PPG INDUSTRIES OHIO, INC. (US) 2021-05-18 US claimed
US-20200165375-A1 \"Polyurethanes, Articles and Coatings Prepared Therefrom and Methods of Making the Same\ PPG INDUSTRIES OHIO, INC. 2020-05-28 US claimed
US-10590230-B2 Polyurethanes, articles and coatings prepared therefrom and methods of making the same PPG INDUSTRIES OHIO, INC. (US) 2020-03-17 US claimed
US-20200071451-A1 Aircraft Windows PPG INDUSTRIES, INC. 2020-03-05 US claimed
CN-105164175-B Polyurethane, product and coating prepared therefrom and its manufacturing method PPG工业俄亥俄公司 2019-06-04 CN claimed
US-20090280329-A1 Polyurethanes, Articles and Coatings Prepared Therefrom and Methods of Making the Same PPG INDUSTRIES OHIO, INC. (US) 2009-11-12 US claimed
US-20090012202-A1 Acrylated Urethanes, Processes for Making the Same and Curable Compositions Including the Same HENKEL CORPORATION (US) 2009-01-08 US claimed
EP-2004720-A2 POLYURETHANES, ARTICLES AND COATINGS PREPARED THEREFROM AND METHODS OF MAKING THE SAME PPG Industries Ohio, Inc. (US) 2008-12-24 EP claimed
US-20070225468-A1 Polyurethanes prepared from polyester polyols and/or polycaprolactone polyols, articles and coatings prepared therefrom and methods of making the same PPG INDUSTRIES OHIO, INC. 2007-09-27 US claimed
US-20070173601-A1 Polyurethanes, articles and coatings prepared therefrom and methods of making the same PPG INDUSTRIES OHIO, INC. 2007-07-26 US claimed
US-20070167600-A1 Polyurethanes prepared from polycaprolactone polyols, articles and coatings prepared therefrom and methods of making the same PPG INDUSTRIES OHIO, INC. 2007-07-19 US claimed
US-20070167601-A1 Polyurethanes prepared from polycarbonate polyols, articles and coatings prepared therefrom and methods of making the same PPG INDUSTRIES OHIO, INC. 2007-07-19 US claimed
US-20070155942-A1 Polyurethanes, articles and coatings prepared therefrom and methods of making the same PPG INDUSTRIES OHIO, INC. 2007-07-05 US claimed
US-20070149749-A1 Polyurethanes prepared from polycarbonate polyols, articles and coatings prepared therefrom and methods of making the same PPG INDUSTRIES OHIO, INC. 2007-06-28 US claimed
WO-2007070627-A2 POLYURETHANES, ARTICLES AND COATINGS PREPARED THEREFROM AND METHODS OF MAKING THE SAME PPG INDUSTRIES OHIO, INC. (US) 2007-06-21 WO claimed