Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4918564 | 0.89 | TSHR (0.43) | ALDH1A1LMNAACHEHSD17B10MAPT | |
| SCHEMBL4910226 | 0.78 | TSHR (0.35) | ALDH1A1LMNAHSD17B10MAPTKMT2A | |
| SCHEMBL2294880 | 0.75 | MAPT (0.35) | ALDH1A1MAPTNPSR1GAASMN1; SMN2 | |
| SCHEMBL130905 | 0.72 | ALDH1A1 (0.58) | ALDH1A1LMNAHSD17B10MAPTKMT2A | |
| SCHEMBL2039663 | 0.72 | CA12 (0.41) | ALDH1A1HSD17B10HPGD | |
| SCHEMBL4914611 | 0.71 | ALDH1A1 (0.32) | ALDH1A1LMNAKMT2A | |
| SCHEMBL168916 | 0.71 | ALDH1A1 (0.35) | ALDH1A1LMNAHSD17B10MAPTKMT2A | |
| SCHEMBL8157465 | 0.71 | ALDH1A1 (0.41) | ALDH1A1LMNAHSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL5134162 | 0.70 | SRC (0.33) | ALDH1A1HSD17B10MAPTTSHRTDP1 | |
| SCHEMBL2534597 | 0.69 | HPGD (0.48) | ALDH1A1LMNAMAPTKMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4056544-A | Anthraquinone compounds | BAYER AKTIENGESELLSCHAFT (DT) | 1977-11-01 | — | — | US | disclosed |