Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4918564 | 0.81 | TSHR (0.43) | ALDH1A1MAPTKMT2AMEN1TSHR | |
| SCHEMBL11855841 | 0.73 | ALDH1A1 (0.41) | ALDH1A1MAPTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL6971754 | 0.72 | IDO1 (0.31) | — | |
| SCHEMBL28961906 | 0.72 | ALDH1A1 (0.41) | ALDH1A1MAPTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL11701641 | 0.71 | ALDH1A1 (0.45) | ALDH1A1MAPTKMT2ASMN1; SMN2TSHR | |
| SCHEMBL9839179 | 0.71 | LMNA (0.52) | ALDH1A1KMT2ASMN1; SMN2MEN1TSHR | |
| SCHEMBL2294880 | 0.70 | MAPT (0.35) | ALDH1A1MAPTSMN1; SMN2TSHRHPGD | |
| SCHEMBL4915979 | 0.69 | — | — | |
| SCHEMBL2039663 | 0.67 | CA12 (0.41) | ALDH1A1HSD17B10HPGD | |
| SCHEMBL129333 | 0.67 | TSHR (0.55) | ALDH1A1MAPTKMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012028100-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-03-08 | — | — | WO | disclosed |