SCHEMBL130905

SCHEMBL130905

CCCOC(=O)c1[c]cccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.58
LMNA P02545 2/20 0.56
TSHR P16473 6/20 0.46
TDP1 Q9NUW8 3/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
ESR1 P03372 1/20 0.46
CHRM1 P11229 1/20 0.46
SLC6A2 P23975 1/20 0.46
KDR P35968 1/20 0.46
CYP3A4 P08684 2/20 0.45
MAPK1 P28482 2/20 0.45
TP53 P04637 1/20 0.45
KDM4E B2RXH2 2/20 0.41
MAOB P27338 2/20 0.41
HSD17B10 Q99714 2/20 0.41
MAPT P10636 2/20 0.41
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.40
THRB P10828 1/20 0.40
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL131719 0.90 TSHR (0.60) ALDH1A1LMNATSHRTDP1L3MBTL1
SCHEMBL11407657 0.89 ALDH1A1 (0.46) ALDH1A1LMNATSHRTDP1L3MBTL1
SCHEMBL4630359 0.89 TSHR (0.61) ALDH1A1LMNATSHRTDP1L3MBTL1
SCHEMBL5145803 0.87 ALDH1A1 (0.62) ALDH1A1LMNATSHRTDP1L3MBTL1
SCHEMBL4630885 0.87 ALDH1A1 (0.62) ALDH1A1LMNATSHRTDP1L3MBTL1
SCHEMBL4698719 0.87 ALDH1A1 (0.62) ALDH1A1LMNATSHRTDP1L3MBTL1
SCHEMBL4623124 0.87 ALDH1A1 (0.62) ALDH1A1LMNATSHRTDP1L3MBTL1
SCHEMBL5144058 0.87 ALDH1A1 (0.62) ALDH1A1LMNATSHRTDP1L3MBTL1
SCHEMBL129333 0.86 TSHR (0.55) ALDH1A1LMNATSHRESR1CYP3A4
SCHEMBL8673620 0.84 TSHR (0.53) ALDH1A1LMNATSHRESR1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7259223-B2 Process for the production of polycarbonate GENERAL ELECTRIC COMPANY (US) 2007-08-21 US claimed
EP-1360220-B1 PROCESS FOR THE PRODUCTION OF POLYCARBONATE GEN ELECTRIC (US) 2007-01-31 EP claimed
US-20040220352-A1 Process for the production of polycarbonate SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2004-11-04 US claimed
EP-1360220-A2 PROCESS FOR THE PRODUCTION OF POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2003-11-12 EP claimed
US-20020132957-A1 Process for the production of polycarbonate GENERAL ELECTRIC COMPANY 2002-09-19 US claimed
WO-2002060855-A2 PROCESS FOR THE PRODUCTION OF POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2002-08-08 WO claimed
EP-0162208-B1 NOVEL N-SUBSTITUTED 3,4-DIHYDROPYRIMIDINE DERIVATIVES, PROCESSES FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS SUNTORY KABUSHIKI KAISHA, also known as SUNTORY LTD. (JP) 1989-11-23 EP claimed
US-4683234-A HYPOTENSIVE AGENTS, ANTI-ANGINA SUNTORY LIMITED (JP) 1987-07-28 US claimed
EP-0162208-A2 Novel N-substituted 3,4-dihydropyrimidine derivatives, processes for preparing them and pharmaceutical compositions SUNTORY KABUSHIKI KAISHA, also known as SUNTORY LTD. (JP) 1985-11-27 EP claimed
US-4214093-A PROTEOLYTIC ENZYME INHIBITORS TORII & CO., LTD. (JP) 1980-07-22 US claimed
CN-117925215-A Electrochromic composition and electrochromic device 泰盈光电股份有限公司 2024-04-26 CN disclosed
US-11886119-B2 Material for forming underlayer film, resist underlayer film, method of producing resist underlayer film, and laminate MITSUI CHEMICALS, INC. (JP) 2024-01-30 US disclosed
CN-110709774-B Underlayer film forming material, resist underlayer film, method for producing resist underlayer film, and laminate 三井化学株式会社 2023-12-08 CN disclosed
US-20230185195-A1 MATERIAL FOR FORMING UNDERLAYER FILM, RESIST UNDERLAYER FILM, METHOD OF PRODUCING RESIST UNDERLAYER FILM, AND LAMINATE MITSUI CHEMICALS, INC. (JP) 2023-06-15 US disclosed
US-11599025-B2 Resin material for forming underlayer film, resist underlayer film, method of producing resist underlayer film, and laminate MITSUI CHEMICALS, INC. (JP) 2023-03-07 US disclosed
EP-0468690-A1 Pyrimidine derivatives SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-01-29 EP disclosed
US-4988662-A MULTILAYER ELEMENT OF A COATED SUBSTRATE, A FILM WITH A COLOR-FORMING LACTONE, AN ACID AND A SENSITIZER DAINIPPON INK AND CHEMICALS, INC. (JP) 1991-01-29 US disclosed
EP-0162208-B1 NOVEL N-SUBSTITUTED 3,4-DIHYDROPYRIMIDINE DERIVATIVES, PROCESSES FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS SUNTORY KABUSHIKI KAISHA, also known as SUNTORY LTD. (JP) 1989-11-23 EP disclosed
US-4214093-A PROTEOLYTIC ENZYME INHIBITORS TORII & CO., LTD. (JP) 1980-07-22 US disclosed
US-3975523-A O-(2-Carbisopropoxyphenyl)-thiono-phosphoric (phosphonic) acid ester-amides and ester-imides and insecticidal and acaricidal composition and method BAYER AKTIENGESELLSCHAFT (DT) 1976-08-17 US disclosed