Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 7/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CFD | P00746 | 1/20 | 0.36 |
| ▸ | F11 | P03951 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19437410 | 0.72 | BRD4 (0.71) | BRD4 | |
| SCHEMBL10587461 | 0.71 | CFD (0.42) | AKR1B1TDP1CFDF11KLKB1 | |
| SCHEMBL10594523 | 0.70 | AKR1B1 (0.37) | AKR1B1TDP1CFDF11KLKB1 | |
| SCHEMBL7082800 | 0.70 | AKR1B1 (0.37) | BRD4AKR1B1TDP1CXCL8 | |
| SCHEMBL10587133 | 0.69 | USP2 (0.44) | TDP1 | |
| SCHEMBL10584219 | 0.69 | AKR1B1 (0.36) | CYP19A1AKR1B1TDP1CFDF11 | |
| SCHEMBL16978818 | 0.68 | KIF11 (0.48) | BRD4CYP19A1 | |
| SCHEMBL7088888 | 0.68 | EDNRA (0.39) | BRD4AKR1B1TDP1CXCL8 | |
| SCHEMBL7081707 | 0.68 | AKR1B1 (0.37) | BRD4AKR1B1TDP1CFDF11 | |
| SCHEMBL3402977 | 0.67 | KDM4C (0.50) | AKR1B1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4013692-A | ANTIINFLAMMATORY, ANTIPYRETICS, ANALGESICS | RIKER LABORATORIES, INC. (US) | 1977-03-22 | — | — | US | disclosed |