Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 3/20 | 0.62 |
| ▸ | CARM1 | Q86X55 | 3/20 | 0.57 |
| ▸ | GNMT | Q14749 | 1/20 | 0.57 |
| ▸ | WDR5 | P61964 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | RBBP5 | Q15291 | 1/20 | 0.56 |
| ▸ | DPY30 | Q9C005 | 1/20 | 0.56 |
| ▸ | ASH2L | Q9UBL3 | 1/20 | 0.56 |
| ▸ | PRKACA | P17612 | 1/20 | 0.55 |
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.54 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11417476 | 0.87 | ADORA2A (0.69) | AHCYKMT2APRKACAADORA3ADORA2A | |
| SCHEMBL11417494 | 0.87 | ADORA2A (0.69) | AHCYKMT2APRKACAADORA3ADORA2A | |
| SCHEMBL11135017 | 0.85 | AHCY (0.71) | AHCYKMT2ADOT1LADORA3ADORA2A | |
| SCHEMBL11135029 | 0.85 | AHCY (0.71) | AHCYKMT2ADOT1LADORA3ADORA2A | |
| SCHEMBL1000839 | 0.85 | ADORA2B (0.69) | AHCYKMT2AADORA3ADORA2AADORA2B | |
| SCHEMBL11413667 | 0.85 | ADORA2B (0.69) | AHCYKMT2AADORA3ADORA2AADORA2B | |
| SCHEMBL11409693 | 0.84 | ADORA3 (0.57) | AHCYKMT2ADOT1LADORA3ADORA2A | |
| SCHEMBL11409684 | 0.84 | ADORA3 (0.57) | AHCYKMT2ADOT1LADORA3ADORA2A | |
| SCHEMBL11701898 | 0.84 | HSP90B1 (0.58) | AHCYKMT2AADORA3ADORA2AADORA2B | |
| SCHEMBL11420629 | 0.83 | AHCY (0.73) | AHCYDOT1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4029884-A | Adenosine-5'-carboxylic acid amides | ABBOTT LABORATORIES (US) | 1977-06-14 | — | — | US | claimed |