Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.72 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | PITRM1 | Q5JRX3 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11703175 | 1.00 | OPRM1 (0.72) | OPRM1OPRK1OPRD1SIGMAR1KDM1A | |
| Dezocine SCHEMBL3072 | 0.84 | OPRM1 (1.00) | OPRM1OPRK1OPRD1SIGMAR1 | |
| Dezocine SCHEMBL11874190 | 0.84 | OPRM1 (1.00) | OPRM1OPRK1OPRD1SIGMAR1 | |
| Dezocine SCHEMBL1369581 | 0.84 | OPRM1 (1.00) | OPRM1OPRK1OPRD1SIGMAR1 | |
| Dezocine SCHEMBL11874182 | 0.84 | OPRM1 (1.00) | OPRM1OPRK1OPRD1SIGMAR1 | |
| Dezocine SCHEMBL9685743 | 0.84 | OPRM1 (1.00) | OPRM1OPRK1OPRD1SIGMAR1 | |
| Dezocine SCHEMBL7781933 | 0.84 | OPRM1 (1.00) | OPRM1OPRK1OPRD1SIGMAR1 | |
| Dezocine SCHEMBL12720257 | 0.84 | OPRM1 (1.00) | OPRM1OPRK1OPRD1SIGMAR1 | |
| Dezocine SCHEMBL21081189 | 0.84 | OPRM1 (1.00) | OPRM1OPRK1OPRD1SIGMAR1 | |
| Dezocine SCHEMBL25583319 | 0.84 | OPRM1 (1.00) | OPRM1OPRK1OPRD1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4049701-A | ANALGESICS, ANTIINFLAMMATORY | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-09-20 | — | — | US | disclosed |
| US-4001326-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-01-04 | — | — | US | disclosed |
| US-4001331-A | ANTIINFLAMMATORY, ANALGESIC | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-01-04 | — | — | US | disclosed |
| US-3979434-A | ANALGESICS, ANTIINFLAMMATORY | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-09-07 | — | — | US | disclosed |
| US-3976696-A | ANALGESIC, ANTIINFLAMMATORY | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-08-24 | — | — | US | disclosed |
| US-3976693-A | ANALGESIC, ANTIINFLAMMATORY | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-08-24 | — | — | US | disclosed |
| US-3957872-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-05-18 | — | — | US | disclosed |
| US-3937736-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-02-10 | — | — | US | disclosed |
| US-3931328-A | CARBURETOR | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-01-06 | — | — | US | disclosed |