Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6096180 | 0.80 | TSHR (0.48) | ALDH1A1TSHRAOC3LMNAL3MBTL1 | |
| SCHEMBL1024967 | 0.77 | ALDH1A1 (0.47) | ALDH1A1TSHRCTSKCTSSAOC3 | |
| SCHEMBL6097351 | 0.77 | ALDH1A1 (0.42) | ALDH1A1TSHRCTSKCTSSAOC3 | |
| SCHEMBL5962473 | 0.76 | TSHR (0.54) | ALDH1A1TSHRAOC3LMNAL3MBTL1 | |
| SCHEMBL6097749 | 0.73 | ALDH1A1 (0.38) | ALDH1A1TSHRAOC3LMNAL3MBTL1 | |
| SCHEMBL6097373 | 0.73 | ALDH1A1 (0.38) | ALDH1A1TSHRAOC3LMNAL3MBTL1 | |
| SCHEMBL20687094 | 0.72 | ALDH1A1 (0.55) | ALDH1A1TSHRCTSKCTSSAOC3 | |
| SCHEMBL22443393 | 0.72 | ALDH1A1 (0.42) | ALDH1A1TSHRCTSKCTSSAOC3 | |
| SCHEMBL13286037 | 0.71 | RIPK1 (0.49) | ALDH1A1TSHRAOC3LMNAL3MBTL1 | |
| SCHEMBL12562387 | 0.71 | TSHR (0.50) | ALDH1A1TSHRAOC3LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4003718-A | Substituted tetrahydropyrimidines | UNIVERSAL OIL PRODUCTS COMPANY (US) | 1977-01-18 | — | — | US | disclosed |