Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | F2R | P25116 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11707458 | 0.88 | MAPK1 (0.59) | HTTALDH1A1GAAMAPK1CYP3A4 | |
| SCHEMBL31435989 | 0.85 | POLB (0.54) | HTTALDH1A1THRBHSD17B10MAPT | |
| SCHEMBL11675911 | 0.85 | POLB (0.54) | HTTALDH1A1THRBHSD17B10MAPT | |
| SCHEMBL11706995 | 0.83 | RAB9A (0.59) | HTTALDH1A1GAAMAPK1CYP3A4 | |
| SCHEMBL11707335 | 0.81 | HTT (0.45) | HTTALDH1A1GAAMAPK1THRB | |
| SCHEMBL11252585 | 0.81 | HTT (0.61) | HTTALDH1A1GAACYP3A4THRB | |
| SCHEMBL716889 | 0.79 | MAPK1 (0.62) | HTTALDH1A1MAPK1FAAHCYP3A4 | |
| SCHEMBL11709369 | 0.79 | KCNK3 (0.64) | ALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL11704390 | 0.79 | CYP1A2 (0.50) | HTTALDH1A1GAATHRBNPC1 | |
| SCHEMBL5768788 | 0.77 | POLB (0.51) | ALDH1A1HSD17B10MAPTMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4036824-A | Disazo dyestuffs containing A-O-alkylene-O-SO3 H group | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-19 | — | — | US | disclosed |