Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 9/20 | 0.64 |
| ▸ | KCNK9 | Q9NPC2 | 7/20 | 0.64 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.57 |
| ▸ | MEN1 | O00255 | 7/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11758098 | 0.92 | HDAC1 (0.54) | KCNK3KCNK9SIRT1KMT2AMEN1 | |
| SCHEMBL7604268 | 0.82 | AKR1C3 (0.56) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31435989 | 0.81 | POLB (0.54) | KMT2AMEN1RAB9ATP53POLB | |
| SCHEMBL11675911 | 0.81 | POLB (0.54) | KMT2AMEN1RAB9ATP53POLB | |
| SCHEMBL11325806 | 0.80 | KCNK3 (0.55) | KCNK3KCNK9SIRT1KMT2AMEN1 | |
| SCHEMBL11707335 | 0.80 | HTT (0.45) | KMT2AMEN1NPC1RAB9AHPGD | |
| SCHEMBL11252585 | 0.80 | HTT (0.61) | KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL2298254 | 0.80 | KCNK3 (1.00) | KCNK3KCNK9SIRT1KMT2AMEN1 | |
| SCHEMBL11705246 | 0.79 | HTT (0.48) | NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL11706995 | 0.79 | RAB9A (0.59) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4036824-A | Disazo dyestuffs containing A-O-alkylene-O-SO3 H group | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-19 | — | — | US | disclosed |