Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.62 |
| ▸ | FAAH | O00519 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | KCNK9 | Q9NPC2 | 4/20 | 0.53 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18814663 | 0.92 | SMN1; SMN2 (0.71) | MAPK1FAAHALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL11283531 | 0.92 | MAPK1 (0.59) | MAPK1FAAHALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL17518820 | 0.92 | MAPK1 (0.55) | MAPK1FAAHALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL11653085 | 0.90 | MGLL (0.58) | MAPK1FAAHALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL8017782 | 0.88 | ALDH1A1 (0.67) | MAPK1FAAHALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL11641473 | 0.88 | MAPK1 (0.55) | MAPK1FAAHALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL2095614 | 0.88 | ALDH1A1 (0.79) | MAPK1FAAHALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL29355426 | 0.88 | ALDH1A1 (0.67) | MAPK1FAAHALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL30589563 | 0.88 | ALDH1A1 (0.79) | MAPK1FAAHALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL9480583 | 0.87 | MAPT (0.69) | MAPK1FAAHALDH1A1CYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023008572-A1 | ONIUM SALT, BLOCKING AGENT DISSOCIATION CATALYST FOR BLOCKED ISOCYANATE, BLOCKED ISOCYANTE COMPOSITION INCLUDING BLOCKING AGENT DISSOCIATION CATALYST, THERMOSETTING RESIN COMPOSITION, AND CURED PRODUCT AND MANUFACTURING METHOD THEREFOR | 広栄化学株式会社 | 2023-02-02 | — | — | WO | disclosed |
| EP-2407449-B1 | ONE-POT PRODUCTION OF CARBAMATES USING SOLID CATALYSTS | CONSEJO SUPERIOR INVESTIGACION (ES) | 2015-01-07 | — | — | EP | disclosed |
| US-8765993-B2 | One-pot production of carbamates using solid catalysts | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 2014-07-01 | — | — | US | disclosed |
| US-8147735-B2 | Semipermeable polymers and method for producing same | ELTRON RESEARCH & DEVELOPMENT, INC. (US) | 2012-04-03 | — | — | US | disclosed |
| US-20120053359-A1 | ONE-POT PRODUCTION OF CARBAMATES USING SOLID CATALYSTS | UNIVERSIDAD POLITECNICA DE VALENCIA (ES) | 2012-03-01 | — | — | US | disclosed |
| EP-2407449-A1 | ONE-POT PRODUCTION OF CARBAMATES USING SOLID CATALYSTS | Consejo Superior de Investigaciones Científicas (CSIC) (ES) | 2012-01-18 | — | — | EP | disclosed |
| US-20100006495-A1 | SEMIPERMEABLE POLYMERS AND METHOD FOR PRODUCING SAME | ELTRON RESEARCH AND DEVELOPMENT, INC. (US) | 2010-01-14 | — | — | US | disclosed |
| EP-0795543-B1 | Use of high boiling solvents or solvent mixtures as heat exchange medium in the thermal decomposition of carbamic esters | BAYER AG (DE) | 2001-10-31 | — | — | EP | disclosed |
| EP-0795544-B1 | Process for the thermal decomposition of carbamic esters | BAYER AG (DE) | 2001-10-31 | — | — | EP | disclosed |
| US-5883291-A | Heat exchange media for the thermal cracking of carbamic acid esters | BAYER AKTIENGESELLSCHAFT (DE) | 1999-03-16 | — | — | US | disclosed |
| EP-0542106-B1 | Process for the preparation of polyisocyanates | BAYER AG (DE) | 1995-12-27 | — | — | EP | disclosed |
| EP-0396977-B1 | Process for the preparation of polyisocyanates | BAYER AG (DE) | 1994-06-15 | — | — | EP | disclosed |
| US-5284969-A | Thermal decomposition of the corresponding carbamic acid esters | BAYER AKTIENGESELLSCHAFT (DE) | 1994-02-08 | — | — | US | disclosed |
| EP-0542106-A2 | Process for the preparation of polyisocyanates | BAYER AG (DE) | 1993-05-19 | — | — | EP | disclosed |
| US-5138015-A | Reacting dialkyl carbonate with diamine to give urethane, thermally decomposing into diisocyanate, coverting into polyurethane in presence of Lewis acid and/or protonic acid | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1992-08-11 | — | — | US | disclosed |
| EP-0477376-A1 | PROCESS FOR PRODUCING POLYURETHANE | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1992-04-01 | — | — | EP | disclosed |
| US-5043471-A | Process for the preparation of polyisocyanates | BAYER AKTIENGESELLSCHAFT (DE) | 1991-08-27 | — | — | US | disclosed |
| EP-0396976-A2 | Process for the preparation of polyisocyanates | BAYER AG (DE) | 1990-11-14 | — | — | EP | disclosed |
| US-4069240-A | GROUP 8 METAL CATALYST | UNIROYAL, INC. (US) | 1978-01-17 | — | — | US | disclosed |
| US-3962302-A | Production of isocyanates from esters of carbamic acids (urethanes) | ATLANTIC RICHFIELD COMPANY (US) | 1976-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053359-A1 | ONE-POT PRODUCTION OF CARBAMATES USING SOLID CATALYSTS | CA7, CA2, CA4 | MAPK1 2842/4885FAAH 2917/4885ALDH1A1 1941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.