SCHEMBL11705271

SCHEMBL11705271

O=C(Cl)Oc1cc(O)cc(OC(=O)Cl)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.38
MEN1 O00255 4/20 0.37
KMT2A Q03164 4/20 0.37
MAPT P10636 2/20 0.37
HPGD P15428 3/20 0.34
ALDH1A1 P00352 2/20 0.34
HSD17B10 Q99714 2/20 0.34
ALOX15 P16050 1/20 0.34
MAPK1 P28482 1/20 0.34
BACE1 P56817 3/20 0.33
CA12 O43570 2/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA7 P43166 2/20 0.33
CA9 Q16790 2/20 0.33
CA14 Q9ULX7 2/20 0.33
HSP90AA1 P07900 1/20 0.33
PTPN1 P18031 1/20 0.33
PTPN11 Q06124 1/20 0.33
HCAR1 Q9BXC0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11703365 0.95 MEN1 (0.41) CYP3A4MEN1KMT2AMAPTHPGD
SCHEMBL998315 0.89 KMT2A (0.39) CYP3A4MEN1KMT2AMAPTALDH1A1
SCHEMBL11700120 0.85 CA12 (0.37) CYP3A4MEN1KMT2AMAPTHPGD
SCHEMBL11703054 0.83 CA12 (0.56) CYP3A4MEN1KMT2AMAPTHPGD
SCHEMBL11699992 0.78 MEN1 (0.32) MEN1KMT2AALDH1A1
SCHEMBL17237455 0.78 KMT2A (0.37) MEN1KMT2AMAPTHPGD
SCHEMBL8165449 0.78 CYP3A4 (0.66) CYP3A4MEN1KMT2AALDH1A1HSD17B10
SCHEMBL1730357 0.77 CYP3A4 (0.43) CYP3A4MEN1KMT2AMAPTHPGD
SCHEMBL5025919 0.76 TPMT (0.44) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL14351002 0.75 CYP3A4 (0.63) CYP3A4MEN1KMT2AMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4059565-A Process for producing a branched polycarbonate or poly(ester-carbonate) MITSUBISHI GAS CHEMICAL COMPANY, INC. (JA) 1977-11-22 US disclosed