SCHEMBL11699992

SCHEMBL11699992

O=C(Cl)Oc1cc(OC(=O)Cl)cc(C(=O)Cl)c1

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ALDH1A1 P00352 2/20 0.31
TSHR P16473 1/20 0.31
GLRA1 P23415 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL890486 0.95 POLB (0.31) ALDH1A1TSHRGLRA1
SCHEMBL998315 0.87 KMT2A (0.39) MEN1KMT2AALDH1A1TSHR
SCHEMBL11702300 0.87 TPMT (0.40) MEN1KMT2AALDH1A1TSHR
SCHEMBL11700120 0.87 CA12 (0.37) MEN1KMT2AALDH1A1GLRA1
SCHEMBL17237455 0.86 KMT2A (0.37) MEN1KMT2A
SCHEMBL5025919 0.84 TPMT (0.44) MEN1KMT2AALDH1A1TSHR
SCHEMBL392901 0.82 LMNA (0.47) MEN1KMT2A
SCHEMBL7753605 0.79 TPMT (0.44) MEN1KMT2AALDH1A1TSHR
SCHEMBL11705271 0.78 CYP3A4 (0.38) MEN1KMT2AALDH1A1
SCHEMBL195019 0.77 LMNA (0.43) MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4059565-A Process for producing a branched polycarbonate or poly(ester-carbonate) MITSUBISHI GAS CHEMICAL COMPANY, INC. (JA) 1977-11-22 US disclosed