Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | LTA4H | P09960 | 7/20 | 0.62 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.62 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.61 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.56 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19322271 | 1.00 | PPARG (0.65) | PPARGNPC1RAB9ALTA4HPLA2G2A | |
| SCHEMBL11857770 | 0.96 | NPC1 (0.69) | PPARGNPC1RAB9ALTA4HPLA2G2A | |
| SCHEMBL9456979 | 0.87 | NPC1 (0.80) | NPC1RAB9ALTA4HFFAR1 | |
| SCHEMBL1070131 | 0.87 | NPC1 (0.73) | NPC1RAB9ALTA4HFFAR1 | |
| SCHEMBL7549790 | 0.86 | LTA4H (0.66) | PPARGNPC1RAB9ALTA4HPLA2G2A | |
| SCHEMBL8671305 | 0.84 | LTA4H (0.75) | LTA4HPLA2G2A | |
| SCHEMBL19322270 | 0.84 | LTA4H (0.67) | LTA4HPLA2G2AFFAR1FFAR4 | |
| SCHEMBL6282133 | 0.83 | NPC1 (0.58) | PPARGNPC1RAB9ALTA4HFFAR1 | |
| Methane SCHEMBL28866356 | 0.83 | NPC1 (0.68) | NPC1RAB9ALTA4HFFAR1 | |
| SCHEMBL28724005 | 0.82 | FFAR1 (0.64) | LTA4HFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4028481-A | ACTIVATED TITANIUM TRICHLORIDE AND AN ORGANOALUMINUM COMPOUND | MITSUI TOATSU CHEMICALS, INCORPORATED (JA) | 1977-06-07 | — | — | US | disclosed |