SCHEMBL19322271

SCHEMBL19322271

c1ccc(Oc2ccc(CCOc3ccc(Oc4ccccc4)cc3)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PPARG P37231 2/20 0.65
NPC1 O15118 1/20 0.63
RAB9A P51151 1/20 0.63
LTA4H P09960 7/20 0.62
PLA2G2A P14555 1/20 0.62
FFAR1 O14842 3/20 0.61
FFAR4 Q5NUL3 1/20 0.56
SLC2A1 P11166 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11705276 1.00 PPARG (0.65) PPARGNPC1RAB9ALTA4HPLA2G2A
SCHEMBL11857770 0.96 NPC1 (0.69) PPARGNPC1RAB9ALTA4HPLA2G2A
SCHEMBL9456979 0.87 NPC1 (0.80) NPC1RAB9ALTA4HFFAR1
SCHEMBL1070131 0.87 NPC1 (0.73) NPC1RAB9ALTA4HFFAR1
SCHEMBL7549790 0.86 LTA4H (0.66) PPARGNPC1RAB9ALTA4HPLA2G2A
SCHEMBL8671305 0.84 LTA4H (0.75) LTA4HPLA2G2A
SCHEMBL19322270 0.84 LTA4H (0.67) LTA4HPLA2G2AFFAR1FFAR4
SCHEMBL6282133 0.83 NPC1 (0.58) PPARGNPC1RAB9ALTA4HFFAR1
Methane SCHEMBL28866356 0.83 NPC1 (0.68) NPC1RAB9ALTA4HFFAR1
SCHEMBL28724005 0.82 FFAR1 (0.64) LTA4HFFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10450408-B2 Method for making polyarylaliphaticetherketone polymers and copolymers thereof KETONEX LIMITED (GB) 2019-10-22 US disclosed
US-20170253696-A1 METHOD FOR MAKING POLYARYLALIPHATICETHERKETONE POLYMERS AND COPOLYMERS THEREOF OXFORD PERFORMANCE MATERIALS, INC 2017-09-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10450408-B2 Method for making polyarylaliphaticetherketone polymers and copolymers thereof DAO, DCXR, LOX PPARG 2070/4885NPC1 4386/4885RAB9A 3590/4885
US-20170253696-A1 METHOD FOR MAKING POLYARYLALIPHATICETHERKETONE POLYMERS AND COPOLYMERS THEREOF COASY, FRK, PBK PPARG 923/4885NPC1 3346/4885RAB9A 3373/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.