Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.66 |
| ▸ | DRD2 | P14416 | 1/20 | 0.62 |
| ▸ | DRD4 | P21917 | 1/20 | 0.62 |
| ▸ | DRD3 | P35462 | 1/20 | 0.62 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.62 |
| ▸ | PPARG | P37231 | 1/20 | 0.61 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.60 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL839323 | 0.92 | DRD2 (0.71) | DRD2DRD4DRD3FFAR1KCNA3 | |
| SCHEMBL11857770 | 0.90 | NPC1 (0.69) | LTA4HDRD2DRD4DRD3FFAR1 | |
| SCHEMBL11705276 | 0.86 | PPARG (0.65) | LTA4HFFAR1PPARGPLA2G2ANPC1 | |
| SCHEMBL19322271 | 0.86 | PPARG (0.65) | LTA4HFFAR1PPARGPLA2G2ANPC1 | |
| SCHEMBL4981505 | 0.85 | KCNA3 (0.73) | DRD2DRD4DRD3FFAR1KCNA3 | |
| SCHEMBL7774931 | 0.84 | PKM (0.68) | FFAR1PPARGPLA2G2A | |
| SCHEMBL12040543 | 0.83 | FFAR1 (0.58) | LTA4HFFAR1 | |
| SCHEMBL4982709 | 0.83 | KCNA3 (0.70) | DRD2DRD4DRD3FFAR1KCNA3 | |
| SCHEMBL19322272 | 0.83 | FFAR1 (0.62) | LTA4HFFAR1PPARG | |
| SCHEMBL2201304 | 0.83 | FFAR1 (0.62) | LTA4HFFAR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1014966-A4 | PHARMACEUTICAL FOR TREATMENT OF NEUROLOGICAL AND NEUROPSYCHIATRIC DISORDERS | ALLELIX NEUROSCIENCE INC (US) | 2001-10-04 | — | — | EP | disclosed |
| EP-1014966-A1 | PHARMACEUTICAL FOR TREATMENT OF NEUROLOGICAL AND NEUROPSYCHIATRIC DISORDERS | Allelix Neuroscience Inc. (US) | 2000-07-05 | — | — | EP | disclosed |
| WO-1997045115-A1 | PHARMACEUTICAL FOR TREATMENT OF NEUROLOGICAL AND NEUROPSYCHIATRIC DISORDERS | TROPHIX PHARMACEUTICALS, INC. (US) | 1997-12-04 | — | — | WO | disclosed |