Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11704660 | 0.89 | NQO2 (0.39) | FABP4SMN1; SMN2NQO2ALDH1A1KDM4E | |
| SCHEMBL11549033 | 0.88 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1KDM4EHPGDTP53 | |
| SCHEMBL11705749 | 0.88 | ACACA (0.44) | FABP4SMN1; SMN2NQO2ALDH1A1NR4A1 | |
| SCHEMBL11560133 | 0.81 | PTGS1 (0.45) | FABP4NQO2ALDH1A1NR4A1NR4A2 | |
| SCHEMBL11705124 | 0.78 | ALDH1A1 (0.43) | FABP4NQO2ALDH1A1NR4A1NR4A2 | |
| SCHEMBL11702889 | 0.77 | ALDH1A1 (0.49) | SMN1; SMN2PDE3AALDH1A1KDM4EPTGS1 | |
| SCHEMBL11703325 | 0.76 | HDAC8 (0.44) | FABP4NQO2ALDH1A1KDM4ETP53 | |
| SCHEMBL11706034 | 0.75 | KDM4E (0.40) | FABP4NQO2ALDH1A1KDM4EPOLB | |
| SCHEMBL11554193 | 0.73 | NR4A1 (0.44) | FABP4SMN1; SMN2NQO2ALDH1A1NR4A1 | |
| SCHEMBL11706498 | 0.73 | CA2 (0.39) | FABP4ALDH1A1NR4A1NR4A2NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4013692-A | ANTIINFLAMMATORY, ANTIPYRETICS, ANALGESICS | RIKER LABORATORIES, INC. (US) | 1977-03-22 | — | — | US | claimed |
| US-4013692-A | ANTIINFLAMMATORY, ANTIPYRETICS, ANALGESICS | RIKER LABORATORIES, INC. (US) | 1977-03-22 | — | — | US | disclosed |