Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.40 |
| ▸ | MAOB | P27338 | 6/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10013355 | 0.83 | MAOA (0.41) | MAOAMAOBSLC6A4SLC6A3HTT | |
| SCHEMBL11702308 | 0.79 | L3MBTL1 (0.44) | MAOAMAOBSLC6A4SLC6A3HPGD | |
| SCHEMBL7287661 | 0.78 | MAPT (0.52) | HPGDUSP2ALDH1A1LMNAPOLB | |
| SCHEMBL7990104 | 0.75 | MAOA (0.56) | MAOAMAOBSLC6A4SLC6A3HPGD | |
| SCHEMBL817735 | 0.74 | MAOA (0.40) | MAOAMAOBSLC6A4SLC6A3USP2 | |
| SCHEMBL1536703 | 0.73 | MAOA (0.56) | MAOAMAOBUSP2ALDH1A1LMNA | |
| SCHEMBL2207700 | 0.71 | KDM4E (0.51) | HPGDALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7984999 | 0.71 | MAOA (0.52) | MAOAMAOBSLC6A4SLC6A3USP2 | |
| SCHEMBL7986401 | 0.71 | MAOA (0.52) | MAOAMAOBSLC6A4SLC6A3USP2 | |
| SCHEMBL818715 | 0.70 | GBA1 (0.47) | MAOAMAOBSLC6A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4036886-A | FROM A PHENYL ALKENYL BROMIDE AND LITHIUM SALT OF A SCHIFF BASE OF ACETALDEHYDE | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1977-07-19 | — | — | US | disclosed |
| US-4031140-A | FLAVORS, ODORS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1977-06-21 | — | — | US | disclosed |