SCHEMBL7990104

SCHEMBL7990104

C=C(CCC(=C)c1ccccc1)c1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 6/20 0.56
MAOB P27338 6/20 0.56
MAPT P10636 3/20 0.45
LMNA P02545 2/20 0.45
MAPK1 P28482 2/20 0.45
USP2 O75604 1/20 0.45
ALDH1A1 P00352 1/20 0.45
POLB P06746 1/20 0.45
HTT P42858 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
SLC6A4 P31645 1/20 0.43
SLC6A3 Q01959 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
NR4A2 P43354 1/20 0.42
KDM4E B2RXH2 1/20 0.42
MEN1 O00255 1/20 0.42
CYP3A4 P08684 1/20 0.42
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7984999 0.89 MAOA (0.52) MAOAMAOBMAPTLMNAMAPK1
SCHEMBL7986401 0.89 MAOA (0.52) MAOAMAOBMAPTLMNAMAPK1
SCHEMBL3383700 0.88 NR4A2 (0.61) MAOAMAOBMAPTLMNAMAPK1
SCHEMBL952229 0.87 MAOA (0.50) MAOAMAOBMAPTLMNAMAPK1
SCHEMBL1005574 0.87 MAOA (0.50) MAOAMAOBMAPTLMNAMAPK1
SCHEMBL7217517 0.87 L3MBTL1 (0.54) MAOAMAOBMAPTLMNAL3MBTL1
SCHEMBL1536703 0.87 MAOA (0.56) MAOAMAOBMAPTLMNAMAPK1
SCHEMBL78217 0.85 CES2 (0.52) MAOAMAOBLMNAL3MBTL1HPGD
SCHEMBL5889400 0.85 MAOA (0.48) MAOAMAOBMAPTLMNAMAPK1
SCHEMBL2064112 0.85 MAOA (0.48) MAOAMAOBMAPTLMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0678526-B1 Ethylene polymers having both ends modified and processes for the production thereof TONEN CORP (JP) 1998-04-01 EP claimed
EP-0678526-A2 Ethylene polymers having both ends modified and processes for the production thereof Tonen Corporation (JP) 1995-10-25 EP claimed
EP-0530408-A1 Olefin polymers having both ends modified and processes for the production thereof Tonen Corporation (JP) 1993-03-10 EP claimed
US-6291068-B1 CORES WITH COATING LAYER, AMMONIUM POLYPHOSPHATE AND THERMOSETTING RESIN, MELAMINE MONOMER OR SURFACE TREATED LAYER CHISSO CORPORATION (JP) 2001-09-18 US disclosed
EP-0924166-A1 THERMOPLASTIC-COATED AMMONIUM POLYPHOSPHATE AND PROCESS FOR THE PREPARATION THEREOF CHISSO CORPORATION (JP) 1999-06-23 EP disclosed
EP-0678526-B1 Ethylene polymers having both ends modified and processes for the production thereof TONEN CORP (JP) 1998-04-01 EP disclosed
EP-0678526-A2 Ethylene polymers having both ends modified and processes for the production thereof Tonen Corporation (JP) 1995-10-25 EP disclosed
EP-0532804-B1 An ethylene polymer and a process for its production TONEN CORP (JP) 1995-06-28 EP disclosed
US-5367033-A Hydroxy or carboxy endcapped polyethylene reacted with diol or diacid TONEN CORPORATION (JP) 1994-11-22 US disclosed
US-5334678-A Using a coordination catalyst containing a vanadium chelate compound and a dialkylaluminum halide TONEN CORPORATION (JP) 1994-08-02 US disclosed
EP-0532804-A1 An ethylene polymer and a process for its production Tonen Corporation (JP) 1993-03-24 EP disclosed
EP-0530408-A1 Olefin polymers having both ends modified and processes for the production thereof Tonen Corporation (JP) 1993-03-10 EP disclosed
US-4571443-A Process for effecting oxidative dehydrodimerization THE STANDARD OIL COMPANY (US) 1986-02-18 US disclosed