Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5375903 | 0.84 | CA1 (0.55) | ALDH1A1MAPTCA1SMN1; SMN2KDM4E | |
| SCHEMBL11794387 | 0.83 | CA1 (0.54) | ALDH1A1MAPTCA1SMN1; SMN2KDM4E | |
| SCHEMBL6676417 | 0.78 | CA1 (0.43) | ALDH1A1OPRM1MAPTCA1SMN1; SMN2 | |
| SCHEMBL6943357 | 0.77 | MAPT (0.46) | ALDH1A1OPRM1OPRD1MAPTCA1 | |
| SCHEMBL6676360 | 0.77 | OPRL1 (0.44) | ALDH1A1TSHROPRM1OPRD1MAPT | |
| SCHEMBL6938929 | 0.76 | MAPT (0.50) | ALDH1A1CYP3A4CYP2C19MAPTCA1 | |
| SCHEMBL6942334 | 0.76 | MAPT (0.50) | ALDH1A1MAPTCA1SMN1; SMN2KDM4E | |
| SCHEMBL6934444 | 0.76 | ALDH1A1 (0.44) | ALDH1A1MAPTCA1SMN1; SMN2KDM4E | |
| SCHEMBL6676434 | 0.75 | ALDH1A1 (0.49) | ALDH1A1OPRM1CA1 | |
| SCHEMBL11709049 | 0.75 | OPRM1 (0.60) | ALDH1A1TSHRCYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4021560-A | ANALGESICS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-05-03 | — | — | US | disclosed |