Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C4 | P17516 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.52 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11700000 | 0.86 | AKR1C4 (0.39) | AKR1C4AKR1C3AKR1C2AKR1C1CASP1 | |
| SCHEMBL95387 | 0.80 | CA1 (0.45) | AKR1C4AKR1C3AKR1C2AKR1C1ALDH1A1 | |
| SCHEMBL423692 | 0.78 | ACLY (0.56) | AKR1C4AKR1C3AKR1C2AKR1C1CASP1 | |
| SCHEMBL30084374 | 0.78 | ACLY (0.56) | AKR1C4AKR1C3AKR1C2AKR1C1CASP1 | |
| SCHEMBL11705279 | 0.76 | TSHR (0.45) | AKR1C4AKR1C3AKR1C2AKR1C1ALDH1A1 | |
| SCHEMBL11704995 | 0.75 | CYP3A4 (0.50) | AKR1C4AKR1C3AKR1C2AKR1C1CASP1 | |
| SCHEMBL1098005 | 0.75 | AKR1C4 (0.52) | AKR1C4AKR1C3AKR1C2AKR1C1CASP1 | |
| Hydrochloric Acid SCHEMBL1097098 | 0.74 | AKR1C4 (0.50) | AKR1C4AKR1C3AKR1C2AKR1C1CASP1 | |
| SCHEMBL11574148 | 0.74 | KDM4E (0.68) | AKR1C4AKR1C3AKR1C2AKR1C1CASP1 | |
| SCHEMBL10722355 | 0.73 | AKR1C4 (0.50) | AKR1C4AKR1C3AKR1C2AKR1C1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4059565-A | Process for producing a branched polycarbonate or poly(ester-carbonate) | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JA) | 1977-11-22 | — | — | US | disclosed |