SCHEMBL95387

SCHEMBL95387

O=COc1c(Cl)cc(Cl)cc1Cl

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA9 Q16790 1/20 0.45
ERN1 O75460 2/20 0.40
ALDH1A1 P00352 6/20 0.39
TDP1 Q9NUW8 1/20 0.38
PPARG P37231 1/20 0.37
TSHR P16473 5/20 0.36
HSD17B10 Q99714 3/20 0.36
CYP3A4 P08684 1/20 0.36
RECQL P46063 1/20 0.36
CYP1A2 P05177 1/20 0.36
ORAI1 Q96D31 1/20 0.33
KMT2A Q03164 2/20 0.33
HPGD P15428 2/20 0.32
AHR P35869 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
KDM4E B2RXH2 1/20 0.32
PTPN1 P18031 1/20 0.32
AKR1C4 P17516 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11705279 0.85 TSHR (0.45) CA1CA2CA9ERN1ALDH1A1
SCHEMBL12040568 0.85 CA1 (0.42) CA1CA2CA9ERN1ALDH1A1
SCHEMBL11024448 0.82 ERN1 (0.46) CA1CA2CA9ERN1ALDH1A1
SCHEMBL11700000 0.80 AKR1C4 (0.39) CA1CA2CA9ERN1ALDH1A1
SCHEMBL11705802 0.80 AKR1C4 (0.52) CA1CA2ALDH1A1TSHRHSD17B10
SCHEMBL16546180 0.76 ERN1 (0.32) ERN1TSHR
SCHEMBL1764467 0.75 CA1 (0.40) CA1CA2CA9ERN1ALDH1A1
SCHEMBL3390853 0.75 CA1 (0.40) CA1CA2CA9ERN1ALDH1A1
SCHEMBL8667994 0.75 ALDH1A1 (0.48) ALDH1A1TDP1TSHRCYP1A2KMT2A
SCHEMBL11783352 0.75 CA1 (0.41) CA1CA2CA9ERN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 263 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119930708-A Preparation method of (3, 3-dimethyl-1-butyne) hexacarbonyl cobalt 上海庆建廷科技有限公司 2025-05-06 CN claimed
US-12091395-B2 Griseofulvin compound DAIICHI SANKYO COMPANY, LIMITED (JP) 2024-09-17 US claimed
US-20240150309-A1 GRISEOFULVIN COMPOUND DAIICHI SANKYO COMPANY, LIMITED (JP) 2024-05-09 US claimed
EP-3109251-B1 METHOD FOR PRODUCING INHIBITOR OF ACTIVATED BLOOD COAGULATION FACTOR X (FXA) DAIICHI SANKYO CO LTD (JP) 2020-07-15 EP claimed
US-20170050983-A1 METHOD FOR PRODUCING INHIBITOR OF ACTIVATED BLOOD COAGULATION FACTOR X (FXA) DAIICHI SANKYO COMPANY, LIMITED (JP) 2017-02-23 US claimed
EP-3109251-A1 METHOD FOR PRODUCING INHIBITOR OF ACTIVATED BLOOD COAGULATION FACTOR X (FXA) DAIICHI SANKYO COMPANY, LIMITED (JP) 2016-12-28 EP claimed
WO-2026107422-A1 6-(PYRIDIN-4-YL)-1H-BENZO[D]IMIDAZOLE DERIVATIVES AS CAMK2 INHIBITORS FOR THE TREATMENT OF HEART FAILURE BRISTOL-MYERS SQUIBB COMPANY (US) 2026-05-21 WO disclosed
WO-2026107424-A1 N-(4-(IMIDAZO[4,5-B]PYRIDIN-5-YL)-2-PYRIDYL)BENZAMIDE DERIVATIVES AS CAMK2 INHIBITORS FOR THE TREATMENT OF HEART FAILURE BRISTOL-MYERS SQUIBB COMPANY (US) 2026-05-21 WO disclosed
US-12606533-B2 3-phenylpropylamine derivative DAIICHI SANKYO COMPANY, LIMITED (JP) 2026-04-21 US disclosed
US-12577217-B2 15-PGDH inhibitor KYORIN PHARMACEUTICAL CO., LTD. (JP) 2026-03-17 US disclosed
US-20260062412-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING MYT1 INHIBITORY ACTIVITY CHUGAI PHARMACEUTICAL CO LTD (JP) 2026-03-05 US disclosed
US-12492187-B2 Factor XI activation inhibitors MERCK SHARP & DOHME LLC (US) 2025-12-09 US disclosed
US-20250353824-A1 3-PHENYLPROPYLAMINE DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2025-11-20 US disclosed
US-4983609-A Anticancer agents OTSUKA PHARMACEUTICAL (JP) 1991-01-08 US disclosed
US-4864021-A ANTICARCINOGENIC AGENTS, ANTITUMOR AGENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1989-09-05 US disclosed
EP-0323441-A2 5-Fluorouracil derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1989-07-05 EP disclosed
EP-0180897-A2 5-Fluorouracil derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1986-05-14 EP disclosed
EP-0180188-A2 A composition for increasing the anti-cancer activity of an anti-cancer compound OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1986-05-07 EP disclosed
US-4259350-A PROTECTING DEGRADABLE ORGANIC MATERIAL FROM FUNGAL OR INSECT ATTACK SANKYO COMPANY LIMITED (JP) 1981-03-31 US disclosed
US-4059565-A Process for producing a branched polycarbonate or poly(ester-carbonate) MITSUBISHI GAS CHEMICAL COMPANY, INC. (JA) 1977-11-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577217-B2 15-PGDH inhibitor PTGDR, ADH1A, ADRA1A CA1 1410/4885CA2 1125/4885CA9 1273/4885
US-12492187-B2 Factor XI activation inhibitors F11, TFPI, F13B CA1 2074/4885CA2 1634/4885CA9 378/4885
US-20250353824-A1 3-PHENYLPROPYLAMINE DERIVATIVE SF1, SF3A1, SFXN1 CA1 4062/4885CA2 4790/4885CA9 4651/4885
US-20240150309-A1 GRISEOFULVIN COMPOUND PTGS1, CYP11B1, GRIA1 CA1 2530/4885CA2 1188/4885CA9 2914/4885
US-20260062412-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING MYT1 INHIBITORY ACTIVITY MYT1, NTMT1, MYL6 CA1 1098/4885CA2 258/4885CA9 1476/4885
US-12606533-B2 3-phenylpropylamine derivative SF3A1, SF1, HTR1D CA1 4656/4885CA2 4713/4885CA9 4828/4885
US-20170050983-A1 METHOD FOR PRODUCING INHIBITOR OF ACTIVATED BLOOD COAGULATION FACTOR X (FXA) F12, F11, F2 CA1 307/4885CA2 308/4885CA9 480/4885
US-12091395-B2 Griseofulvin compound PTGS1, CYP11B1, GRIA1 CA1 2530/4885CA2 1188/4885CA9 2914/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.