Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 5/20 | 0.89 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.73 |
| ▸ | ALDH2 | P05091 | 6/20 | 0.73 |
| ▸ | PHGDH | O43175 | 3/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.64 |
| ▸ | GMNN | O75496 | 1/20 | 0.64 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.64 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.64 |
| ▸ | HTR1A | P08908 | 1/20 | 0.64 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.64 |
| ▸ | FBP1 | P09467 | 1/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11009694 | 0.98 | MGLL (0.85) | MGLLALDH1A1ALDH2PHGDHCYP3A4 | |
| SCHEMBL15157784 | 0.94 | MGLL (0.84) | MGLLALDH1A1ALDH2PHGDHCYP3A4 | |
| SCHEMBL8468348 | 0.94 | MGLL (0.84) | MGLLALDH1A1ALDH2PHGDHCYP3A4 | |
| SCHEMBL448863 | 0.94 | MGLL (0.84) | MGLLALDH1A1ALDH2PHGDHCYP3A4 | |
| SCHEMBL15158100 | 0.94 | MGLL (0.84) | MGLLALDH1A1ALDH2PHGDHCYP3A4 | |
| SCHEMBL11010068 | 0.94 | MGLL (0.84) | MGLLALDH1A1ALDH2PHGDHCYP3A4 | |
| SCHEMBL6417261 | 0.94 | MGLL (0.84) | MGLLALDH1A1ALDH2PHGDHCYP3A4 | |
| SCHEMBL5410089 | 0.94 | MGLL (0.84) | MGLLALDH1A1ALDH2PHGDHCYP3A4 | |
| SCHEMBL284494 | 0.94 | MGLL (0.84) | MGLLALDH1A1ALDH2PHGDHCYP3A4 | |
| Disulfiram SCHEMBL15633014 | 0.92 | ALDH1A1 (0.87) | MGLLALDH1A1ALDH2PHGDHCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4006140-A | AGING RESISTANCE IMPROVERS FOR VULCANIZABLE RUBBERS | THE B. F. GOODRICH COMPANY (US) | 1977-02-01 | — | — | US | disclosed |