Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | GABRA3 | P34903 | 8/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GPR39 | O43194 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | S100A4 | P26447 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11111467 | 0.88 | ADRA1A (0.52) | ADRA1AGABRA3GABRA2GABRA1GABRA5 | |
| SCHEMBL24127983 | 0.85 | ADRA1A (0.50) | ADRA1AGABRA3GABRA2GABRA1GABRA5 | |
| SCHEMBL11830130 | 0.85 | ADRA1A (0.47) | ADRA1AGABRA3GABRA2GABRA1GABRA5 | |
| SCHEMBL29783067 | 0.84 | ADRA1A (0.46) | ADRA1AGABRA3GABRA2GABRA1GABRA5 | |
| SCHEMBL19484879 | 0.84 | ADRA1A (0.46) | ADRA1AGABRA3GABRA2GABRA1GABRA5 | |
| SCHEMBL7313069 | 0.83 | ADRA1A (0.50) | ADRA1AGABRA3GABRA2GABRA1GABRA5 | |
| SCHEMBL11728322 | 0.83 | ADRA1A (0.50) | ADRA1AGABRA3GABRA2GABRA1GABRA5 | |
| SCHEMBL11851203 | 0.83 | ADRA1A (0.45) | ADRA1AGABRA3GABRA2GABRA1GABRA5 | |
| SCHEMBL2841206 | 0.83 | GABRA1 (0.49) | GABRA3GABRA2GABRA1GABRA5GABRB2 | |
| SCHEMBL7372472 | 0.81 | ADRA1A (0.58) | ADRA1AGABRA3GABRA2GABRA1GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021256679-A1 | PREPARATION METHOD OF 3-[(4S)-8-BROMO-1-METHYL-6-(2-PYRIDINYL)-4H-IMIDAZO[1,2-A][1,4]BENZODIAZEPINE-4-YL]PROPIONIC ACID METHYL ESTER | 하나제약 주식회사 | 2021-12-23 | — | — | WO | disclosed |
| US-4044016-A | ANTICONVULSANTS, SEDATIVES, MUSCLE RELAXANTS | HOFFMANN-LA ROCHE INC. (US) | 1977-08-23 | — | — | US | disclosed |
| US-3970664-A | ANTICONVULSANT, MUSCLE RELAXANT, SEDATIVE | HOFFMANN-LA ROCHE INC. (US) | 1976-07-20 | — | — | US | disclosed |
| US-3954728-A | ANTICONVULSANTS, MUSCLE RELAXANTS, SEDATIVES | HOFFMAN-LA ROCHE INC. (US) | 1976-05-04 | — | — | US | disclosed |