Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.72 |
| ▸ | ESRRB | O95718 | 1/20 | 0.63 |
| ▸ | ESRRG | P62508 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | CA1 | P00915 | 2/20 | 0.62 |
| ▸ | CA2 | P00918 | 2/20 | 0.62 |
| ▸ | CA5A | P35218 | 1/20 | 0.62 |
| ▸ | CA7 | P43166 | 1/20 | 0.62 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.60 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.60 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.60 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4152627 | 0.95 | TRPV1 (0.78) | TRPV1ESRRBESRRGHPGDGAA | |
| SCHEMBL4152553 | 0.95 | TRPV1 (0.78) | TRPV1ESRRBESRRGHPGDGAA | |
| SCHEMBL4161209 | 0.89 | ESRRB (0.77) | TRPV1ESRRBESRRGHPGDGAA | |
| SCHEMBL4153733 | 0.87 | HPGD (0.79) | TRPV1HPGDGAACA1CA2 | |
| SCHEMBL13960177 | 0.84 | ALDH1A1 (0.84) | TRPV1GAACA1CA2CA5A | |
| SCHEMBL13960176 | 0.84 | ALDH1A1 (0.84) | TRPV1GAACA1CA2CA5A | |
| SCHEMBL4151976 | 0.83 | GAA (0.74) | TRPV1HPGDGAAMEN1KMT2A | |
| SCHEMBL4151866 | 0.83 | GAA (0.74) | TRPV1HPGDGAAMEN1KMT2A | |
| SCHEMBL22664772 | 0.81 | CA1 (0.69) | TRPV1HPGDGAACA1CA2 | |
| SCHEMBL8803541 | 0.81 | LTA4H (0.79) | TRPV1HPGDGAACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4010279-A | BIPHENYLOXY DERIVATIVES AND ANTIHYPERLIPIDEMIC USE | BOEHRINGER INGELHEIM GMBH (DT) | 1977-03-01 | — | — | US | disclosed |