SCHEMBL11706397

SCHEMBL11706397

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C=CI

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35
THRB P10828 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31269501 1.00 LMNA (0.35) LMNATHRB
SCHEMBL4045868 0.97 THRB (0.31) LMNATHRB
SCHEMBL3997608 0.88
SCHEMBL10791767 0.82 LMNA (0.42) LMNATHRB
SCHEMBL8963077 0.82
SCHEMBL31638108 0.82 LMNA (0.42) LMNATHRB
SCHEMBL11769431 0.82 LMNA (0.42) LMNATHRB
SCHEMBL1904446 0.82 LMNA (0.42) LMNATHRB
SCHEMBL1904448 0.82 LMNA (0.42) LMNATHRB
SCHEMBL8963061 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4058573-A FREE RADICAL CATALYST CIBA-GEIGY CORPORATION (US) 1977-11-15 US disclosed