⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963061 | 1.00 | — | — | |
| SCHEMBL3997608 | 0.87 | — | — | |
| SCHEMBL4045868 | 0.84 | THRB (0.31) | — | |
| SCHEMBL11706397 | 0.82 | LMNA (0.35) | — | |
| SCHEMBL31269501 | 0.82 | LMNA (0.35) | — | |
| SCHEMBL31135173 | 0.79 | — | — | |
| SCHEMBL4067895 | 0.78 | KDM4E (0.31) | — | |
| SCHEMBL3836394 | 0.73 | — | — | |
| SCHEMBL757563 | 0.69 | — | — | |
| SCHEMBL757565 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0504322-B1 | PARTIALLY FLUORINATED COMPOUNDS AND POLYMERS | DU PONT (US) | 1996-02-14 | — | — | EP | disclosed |
| US-5286825-A | Copolymer of tetrafluoroethylene and bis-2,2-trifluoromethyl-4,5-difluorodivinyl-1,3-dioxolanes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-02-15 | — | — | US | disclosed |
| US-5233058-A | Fluoro-2,2-dimethyldioxolanes; copolymers with tetrafluoroethylene | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-08-03 | — | — | US | disclosed |