Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.64 |
| ▸ | RAB9A | P51151 | 8/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | SCD | O00767 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11707254 | 0.91 | NPC1 (0.64) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11705219 | 0.86 | NPC1 (0.56) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11706151 | 0.85 | NPC1 (0.72) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11707745 | 0.79 | NPC1 (0.71) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11206434 | 0.78 | NPC1 (1.00) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10742942 | 0.78 | ACR (0.53) | NPC1KMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL11705235 | 0.77 | HDAC6 (0.59) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11706161 | 0.77 | NPC1 (0.72) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11094182 | 0.77 | ACR (0.52) | NPC1KMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL11094782 | 0.77 | ACR (0.52) | NPC1KMT2AMEN1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4011236-A | N-(BENZIMIDAZOL-2-YL)ARYLCARBOXAMIDES AS ULTRAVIOLET (UV) LIGHT ABSORBERS | MERCK & CO., INC. (US) | 1977-03-08 | — | — | US | disclosed |