SCHEMBL11707698

SCHEMBL11707698

Nc1cc(Cl)c(OCCO)cc1Cl

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.46
MAOA P21397 3/20 0.43
NPC1 O15118 1/20 0.42
LMNA P02545 2/20 0.38
ALDH1A1 P00352 1/20 0.38
DHFR P00374 2/20 0.38
IDO1 P14902 1/20 0.37
LOX P28300 1/20 0.36
AOC3 Q16853 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10889603 0.89 GAA (0.41) GAAMAOANPC1LMNAALDH1A1
SCHEMBL11069560 0.88 ALDH1A1 (0.44) LMNAALDH1A1DHFRIDO1LOX
Hydrochloric Acid SCHEMBL10887528 0.87 GAA (0.39) GAAMAOANPC1ALDH1A1LOX
SCHEMBL11794328 0.84 CD44 (0.39) GAAMAOANPC1LMNAALDH1A1
SCHEMBL29444902 0.84 LMNA (0.48) MAOALMNAALDH1A1DHFRIDO1
SCHEMBL4897444 0.84 LMNA (0.48) MAOALMNAALDH1A1DHFRIDO1
SCHEMBL134595 0.84 LMNA (0.48) MAOALMNAALDH1A1DHFRIDO1
SCHEMBL6815691 0.82 GAA (0.65) GAAMAOANPC1ALDH1A1
SCHEMBL3343161 0.80 MAOA (0.40) GAAMAOANPC1LMNAALDH1A1
SCHEMBL3342137 0.80 MAOA (0.38) MAOANPC1LMNAALDH1A1DHFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4036824-A Disazo dyestuffs containing A-O-alkylene-O-SO3 H group BAYER AKTIENGESELLSCHAFT (DT) 1977-07-19 US disclosed
US-3956267-A Indole-containing disazo dyestuffs having a sulfatoalkyleneoxy-substituent BAYER AKTIENGESELLSCHAFT (DT) 1976-05-11 US disclosed