Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CDC7 | O00311 | 1/20 | 0.30 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11711212 | 0.86 | L3MBTL1 (0.42) | HAO1HSD17B10MAOAMAOBP2RY6 | |
| SCHEMBL11708209 | 0.85 | SMN1; SMN2 (0.41) | HAO1HSD17B10P2RY6MIFALDH1A1 | |
| SCHEMBL11708734 | 0.84 | MIF (0.46) | HSD17B10P2RY6MIFALDH1A1HTT | |
| SCHEMBL11705515 | 0.81 | MAPT (0.33) | HAO1HSD17B10P2RY6ALDH1A1 | |
| SCHEMBL11709012 | 0.78 | P2RY6 (0.44) | HSD17B10MAOBP2RY6ALDH1A1LMNA | |
| SCHEMBL11706471 | 0.74 | SMN1; SMN2 (0.52) | MIFALDH1A1MEN1KMT2A | |
| SCHEMBL11706465 | 0.74 | P2RY6 (0.38) | HSD17B10P2RY6MIF | |
| SCHEMBL11710518 | 0.72 | LRRK2 (0.38) | HSD17B10P2RY6ALDH1A1LMNANPSR1 | |
| SCHEMBL6699101 | 0.72 | L3MBTL1 (0.56) | HSD17B10P2RY6MIFALDH1A1NPSR1 | |
| SCHEMBL1019382 | 0.72 | MIF (0.56) | HSD17B10EGFRP2RY6MIFALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4001254-A | ISOTHIOCYANOPYRIDINE DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1977-01-04 | — | — | US | disclosed |