Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 4/20 | 0.76 |
| ▸ | PDE5A | O76074 | 1/20 | 0.72 |
| ▸ | AKT1 | P31749 | 2/20 | 0.69 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.68 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.64 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.64 |
| ▸ | PIM1 | P11309 | 2/20 | 0.64 |
| ▸ | CD38 | P28907 | 2/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.63 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.62 |
| ▸ | FASN | P49327 | 3/20 | 0.62 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.62 |
| ▸ | SI | P14410 | 3/20 | 0.62 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.62 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.62 |
| ▸ | IDH1 | O75874 | 2/20 | 0.62 |
| ▸ | PGAM1 | P18669 | 2/20 | 0.62 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26621024 | 0.91 | MGAM (0.73) | MGAMPDE5AAKT1ABCG2PTPN1 | |
| SCHEMBL24075660 | 0.91 | MGAM (0.80) | MGAMPDE5AAKT1ABCG2PTPN1 | |
| SCHEMBL29833229 | 0.91 | MGAM (0.80) | MGAMPDE5AAKT1ABCG2PTPN1 | |
| SCHEMBL6822263 | 0.91 | ABCG2 (0.84) | MGAMPDE5AAKT1ABCG2PTPN1 | |
| SCHEMBL6822261 | 0.91 | ABCG2 (0.84) | MGAMPDE5AAKT1ABCG2PTPN1 | |
| Licoflavonol SCHEMBL29392785 | 0.90 | ABCG2 (0.82) | MGAMPDE5AAKT1ABCG2PTPN1 | |
| Licoflavonol SCHEMBL8050093 | 0.90 | ABCG2 (0.82) | MGAMPDE5AAKT1ABCG2PTPN1 | |
| SCHEMBL26621022 | 0.89 | MGAM (0.72) | MGAMPDE5AAKT1ABCG2PTPN1 | |
| SCHEMBL30020726 | 0.88 | PTPN1 (0.67) | MGAMPDE5AABCG2PTPN1PDE4D | |
| SCHEMBL30766286 | 0.88 | PTPN1 (0.83) | MGAMPDE5AAKT1PTPN1PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11795127-B2 | Processes for the preparation of ortho-allylated hydroxy aryl compounds | MCMASTER UNIVERSITY (CA) | 2023-10-24 | — | — | US | disclosed |
| US-20230113567-A1 | PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS | MCMASTER UNIVERSITY (CA) | 2023-04-13 | — | — | US | disclosed |
| US-20210380513-A1 | PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS | MCMASTER UNIVERSITY (CA) | 2021-12-09 | — | — | US | disclosed |
| WO-2021237371-A1 | PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS | MCMASTER UNIVERSITY (CA) | 2021-12-02 | — | — | WO | disclosed |
| WO-2021125342-A1 | COMPOSITION FOR SUPPRESSING OBESITY | 株式会社ダイセル | 2021-06-24 | — | — | WO | disclosed |
| US-7888388-B2 | Peroxisome proliferator activated receptor ligand and process for producing the same | KANEKA CORPORATION (JP) | 2011-02-15 | — | — | US | disclosed |
| US-7524975-B2 | Peroxisome proliferator activated receptor ligand and process for producing the same | KANEKA CORPORATION (JP) | 2009-04-28 | — | — | US | disclosed |
| US-20090036519-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR LIGAND AND PROCESS FOR PRODUCING THE SAME | KANEKA CORPORATION (JP) | 2009-02-05 | — | — | US | disclosed |
| CN-1599602-A | Peroxisome proliferator activated receptor ligands and process for producing the same | KANEGAFUCHI CHEMICAL IND (JP) | 2005-03-23 | — | — | CN | disclosed |
| US-20050014819-A1 | Peroxisome proliferator activated receptor ligands and process for producing the same | KANEKA CORPORATION (JP) | 2005-01-20 | — | — | US | disclosed |
| EP-1440688-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR LIGANDS AND PROCESS FOR PRODUCING THE SAME | KANEKA CORPORATION (JP) | 2004-07-28 | — | — | EP | disclosed |
| US-6737439-B2 | ACTIVE CANCER CHEMOPREVENTATIVE AND TREATING AGENTS IN MAMMALS, INCLUDING HUMANS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2004-05-18 | — | — | US | disclosed |
| US-20030125377-A1 | Aromatase inhibitors from Broussonetia papyrifera | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS THE | 2003-07-03 | — | — | US | disclosed |
| WO-2003013554-A2 | AROMATASE INHIBITORS FROM BROUSSONETIA PAPYRIFERA | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2003-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230113567-A1 | PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS | ADH1A, ADH1C, AHR | MGAM 3381/4885PDE5A 4858/4885AKT1 972/4885 |
| US-20030125377-A1 | Aromatase inhibitors from Broussonetia papyrifera | CYP19A1, HSD17B11, CYP17A1 | MGAM 1782/4885PDE5A 414/4885AKT1 956/4885 |
| US-20210380513-A1 | PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS | ADH1A, ADH1C, AHR | MGAM 3381/4885PDE5A 4858/4885AKT1 972/4885 |
| US-20090036519-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR LIGAND AND PROCESS FOR PRODUCING THE SAME | PPARG, PPARA, PPARD | MGAM 1182/4885PDE5A 3857/4885AKT1 1023/4885 |
| US-11795127-B2 | Processes for the preparation of ortho-allylated hydroxy aryl compounds | ADH1A, ADH1C, AHR | MGAM 3381/4885PDE5A 4858/4885AKT1 972/4885 |
| US-20050014819-A1 | Peroxisome proliferator activated receptor ligands and process for producing the same | PPARG, PPARA, PPARD | MGAM 1180/4885PDE5A 3588/4885AKT1 1021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.