Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | EBP | Q15125 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL11719164 | 0.94 | POLB (0.48) | KCNH2ADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL30134682 | 0.90 | HRH3 (0.51) | KCNH2ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL11708757 | 0.90 | SIGMAR1 (0.50) | ADRA1DADRA1AADRA1BMAPTSIGMAR1 | |
| SCHEMBL11712922 | 0.90 | MAPT (0.45) | KCNH2ADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL11715311 | 0.89 | DHCR7 (0.49) | KCNH2ADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL11712332 | 0.88 | CYP1A2 (0.44) | KCNH2ADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL30166688 | 0.87 | MAPT (0.43) | MAPTCYP1A2HTR1ASIGMAR1GAA | |
| SCHEMBL11708040 | 0.87 | CYP1A2 (0.62) | CYP1A2HTR1ASIGMAR1 | |
| SCHEMBL11710137 | 0.86 | DHCR7 (0.50) | ADRA1DADRA1AADRA1BMAPTSIGMAR1 | |
| SCHEMBL29362528 | 0.86 | DHCR7 (0.50) | ADRA1DADRA1AADRA1BMAPTSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4035363-A | 1,3-BENZOXAZINE DERIVATIVES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1977-07-12 | — | — | US | claimed |
| US-4035363-A | 1,3-BENZOXAZINE DERIVATIVES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1977-07-12 | — | — | US | disclosed |