Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11708757 | 0.90 | SIGMAR1 (0.50) | MAPTABCB1HRH3ADRA1DADRA1A | |
| SCHEMBL11709331 | 0.90 | KCNH2 (0.50) | MAPTKCNH2ADRA1DADRA1AADRA1B | |
| SCHEMBL11715311 | 0.89 | DHCR7 (0.49) | MAPTABCB1CYP3A4KCNH2ADRA1D | |
| SCHEMBL29362528 | 0.87 | DHCR7 (0.50) | MAPTABCB1ADRA1DADRA1AADRA1B | |
| SCHEMBL11710137 | 0.87 | DHCR7 (0.50) | MAPTABCB1ADRA1DADRA1AADRA1B | |
| Oxalic Acid SCHEMBL11719164 | 0.85 | POLB (0.48) | MAPTABCB1KCNH2ADRA1DADRA1A | |
| SCHEMBL30134682 | 0.83 | HRH3 (0.51) | ABCB1HRH3KCNH2ADRA1DADRA1A | |
| SCHEMBL30166688 | 0.82 | MAPT (0.43) | MAPTHRH3 | |
| SCHEMBL11712113 | 0.80 | SIGMAR1 (0.43) | MAPTKCNH2 | |
| SCHEMBL11707373 | 0.79 | MAPT (0.51) | MAPTABCB1HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4035363-A | 1,3-BENZOXAZINE DERIVATIVES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1977-07-12 | — | — | US | claimed |
| US-4035363-A | 1,3-BENZOXAZINE DERIVATIVES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1977-07-12 | — | — | US | disclosed |