Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.51 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11709331 | 0.90 | KCNH2 (0.50) | SIGMAR1KCNH2HTR1ADRD2ADRA1D | |
| SCHEMBL11708757 | 0.88 | SIGMAR1 (0.50) | HRH3ABCB1SIGMAR1ADRA1DADRA1A | |
| Oxalic Acid SCHEMBL11719164 | 0.85 | POLB (0.48) | ABCB1SIGMAR1KCNH2HTR1ADRD2 | |
| SCHEMBL11712922 | 0.83 | MAPT (0.45) | HRH3ABCB1KCNH2ADRA1DADRA1A | |
| SCHEMBL11715311 | 0.82 | DHCR7 (0.49) | ABCB1KCNH2ADRA1DADRA1AADRA1B | |
| SCHEMBL11712332 | 0.81 | CYP1A2 (0.44) | KCNH2DRD2ADRA1DADRA1AADRA1B | |
| SCHEMBL11710137 | 0.80 | DHCR7 (0.50) | ABCB1SIGMAR1ADRA1DADRA1AADRA1B | |
| SCHEMBL29362528 | 0.80 | DHCR7 (0.50) | ABCB1SIGMAR1ADRA1DADRA1AADRA1B | |
| SCHEMBL30166688 | 0.78 | MAPT (0.43) | HRH3SIGMAR1HTR1A | |
| SCHEMBL11708040 | 0.78 | CYP1A2 (0.62) | REV1SIGMAR1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230150935-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING CALCIUM ION HOMEOSTASIS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-05-18 | — | — | US | disclosed |
| EP-4103551-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING CALCIUM ION HOMEOSTASIS | The Regents of the University of California (US) | 2022-12-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150935-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING CALCIUM ION HOMEOSTASIS | CHERP, ATP2A1, ATP2A3 | HRH3 3499/4885REV1 2530/4885NPC1 352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.