Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | ENPP1 | P22413 | 7/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11711194 | 0.86 | ALDH1A1 (0.47) | ALDH1A1ENPP1L3MBTL1LMNAGAA | |
| SCHEMBL1646899 | 0.78 | ALDH1A1 (0.50) | ALDH1A1ENPP1L3MBTL1LMNAGAA | |
| SCHEMBL11709565 | 0.72 | — | — | |
| SCHEMBL7819692 | 0.72 | TSHR (0.50) | ALDH1A1ENPP1LMNAKMT2AMEN1 | |
| SCHEMBL5674713 | 0.72 | ALDH1A1 (0.47) | ALDH1A1ENPP1L3MBTL1LMNAGAA | |
| SCHEMBL5324250 | 0.71 | MBOAT4 (0.40) | ALDH1A1ENPP1L3MBTL1LMNAGAA | |
| SCHEMBL24127885 | 0.70 | ENPP1 (0.59) | ALDH1A1ENPP1L3MBTL1LMNAGAA | |
| SCHEMBL7117782 | 0.69 | ALDH1A1 (0.44) | ALDH1A1ENPP1L3MBTL1LMNAGAA | |
| SCHEMBL20482747 | 0.69 | ALDH1A1 (0.46) | ALDH1A1ENPP1L3MBTL1LMNAGAA | |
| SCHEMBL24127923 | 0.69 | ENPP1 (0.57) | ALDH1A1ENPP1L3MBTL1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4007189-A | VASODILATION, HYPOTENSIVE | SANKYO COMPANY LIMITED (JA) | 1977-02-08 | — | — | US | disclosed |