Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11811956 | 0.88 | KDM4E (0.59) | KDM4ESMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL6068444 | 0.88 | ALDH1A1 (0.48) | TP53KDM4ESMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL11708570 | 0.85 | ALDH1A1 (0.47) | NPC1RAB9AS1PR5KDM4EMEN1 | |
| SCHEMBL11706921 | 0.83 | ALDH1A1 (0.46) | TP53KDM4ESMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL10841567 | 0.79 | RORC (0.52) | NPC1KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL11707386 | 0.79 | MAPT (0.56) | KDM4ESMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL11708246 | 0.79 | SIGMAR1 (0.48) | KDM4EMEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL3177594 | 0.77 | GRM2 (0.60) | NPC1RAB9AHRH3S1PR5TP53 | |
| SCHEMBL11708814 | 0.77 | MAOB (0.51) | NPC1RAB9AMAOBHRH3S1PR5 | |
| SCHEMBL28079581 | 0.76 | HRH3 (0.48) | NPC1RAB9AMAOBHRH3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4012389-A | ANTICOAGULANTS | DONAU-PHARMAZIE GESELLSCHAFT M.B.H. (OE) | 1977-03-15 | — | — | US | disclosed |
| US-3935214-A | ANTICOAGULANT | DONAU-PHARMAZIE GESELLSCHAFT M.B.H. (OE) | 1976-01-27 | — | — | US | disclosed |