SCHEMBL11711571

SCHEMBL11711571

Cc1ccc2cc(-c3ccccc3-c3ccccc3)oc2c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 5/20 0.57
MAOA P21397 2/20 0.51
KDM4E B2RXH2 3/20 0.44
HPGD P15428 2/20 0.44
ALDH1A1 P00352 1/20 0.44
TP53 P04637 1/20 0.44
CYP3A4 P08684 1/20 0.44
MAPT P10636 1/20 0.44
HSD17B10 Q99714 1/20 0.44
RAB9A P51151 3/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
NPC1 O15118 4/20 0.43
POLB P06746 3/20 0.43
CASP3 P42574 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
SENP8 Q96LD8 1/20 0.43
SENP7 Q9BQF6 1/20 0.43
SENP6 Q9GZR1 1/20 0.43
PGR P06401 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11713027 0.86 MAOB (0.74) MAOBMAOAKDM4EHPGDALDH1A1
SCHEMBL11711558 0.83 MAOB (0.70) MAOBMAOAKDM4EHPGDALDH1A1
SCHEMBL727203 0.81 MAOB (0.62) MAOBMAOAKDM4EHPGDALDH1A1
SCHEMBL14231752 0.78 MAOB (0.50) MAOBMAOAKDM4EALDH1A1MAPT
SCHEMBL27106348 0.78 MAOB (0.49) MAOBMAOAKDM4EALDH1A1CYP3A4
SCHEMBL12304339 0.77 MAOB (0.77) MAOBMAOAKDM4EALDH1A1RAB9A
SCHEMBL733971 0.75 MAOB (0.61) MAOBMIF
SCHEMBL21747478 0.75 MAOB (0.57) MAOBMAOAHPGDALDH1A1CYP3A4
SCHEMBL21860453 0.74 MAOB (0.56) MAOBKDM4EHPGDALDH1A1TP53
SCHEMBL21860428 0.74 MAOB (0.56) MAOBKDM4EHPGDALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4013642-A OPTICAL BRIGHTENERS CIBA-GEIGY CORPORATION (US) 1977-03-22 US disclosed