Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | GABRP | O00591 | 1/20 | 0.50 |
| ▸ | GABRD | O14764 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.50 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.50 |
| ▸ | GABRE | P78334 | 1/20 | 0.50 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.50 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547983 | 0.89 | MAOB (0.72) | MAOBALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL9754513 | 0.84 | ALDH1A1 (0.67) | MAOBALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL21747480 | 0.80 | ALDH1A1 (0.52) | MAOBALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL16894626 | 0.80 | ALDH1A1 (0.74) | MAOBALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL27106348 | 0.75 | MAOB (0.49) | MAOBALDH1A1MAOAPOLBCYP3A4 | |
| SCHEMBL11711571 | 0.75 | MAOB (0.57) | MAOBALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL3051786 | 0.73 | MMP2 (0.61) | MAOBALDH1A1KMT2AMEN1GAA | |
| SCHEMBL14231752 | 0.73 | MAOB (0.50) | MAOBALDH1A1MAOAMAPTPDE4B | |
| SCHEMBL9571333 | 0.72 | GABRP (0.53) | MAOBALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL1459318 | 0.71 | ALDH1A1 (1.00) | ALDH1A1LMNAKMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3613735-B1 | NOVEL SIRT 1 ACTIVATOR AND MEDICINAL USE THEREOF | NAT UNIV PUSAN IND UNIV COOP FOUND (KR) | 2023-04-12 | — | — | EP | disclosed |
| EP-3613735-A1 | NOVEL SIRT 1 ACTIVATOR AND MEDICINAL USE THEREOF | Pusan National University Industry - University Cooperation Foundation (KR) | 2020-02-26 | — | — | EP | disclosed |