Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 12/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.49 |
| ▸ | CBR1 | P16152 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27911213 | 0.86 | CA1 (0.50) | MRGPRX4MAPTHPGDSMN1; SMN2MEN1 | |
| SCHEMBL8618574 | 0.82 | MRGPRX4 (0.62) | MRGPRX4MAPTHPGDSMN1; SMN2ADRB2 | |
| SCHEMBL16015951 | 0.81 | MRGPRX4 (0.61) | MRGPRX4 | |
| SCHEMBL9615329 | 0.81 | FABP3 (0.57) | MRGPRX4MAPTHPGDSMN1; SMN2MEN1 | |
| SCHEMBL2561433 | 0.80 | MRGPRX4 (0.60) | MRGPRX4MAPTADRB2TDP1SLC6A2 | |
| SCHEMBL8783044 | 0.79 | MRGPRX4 (0.80) | MRGPRX4ADRB2TDP1CHRM1NPC1 | |
| SCHEMBL22480892 | 0.79 | MRGPRX4 (1.00) | MRGPRX4MEN1ALDH1A1KMT2ANPC1 | |
| SCHEMBL8590603 | 0.77 | MRGPRX4 (0.57) | MRGPRX4MAPTHPGDSMN1; SMN2MEN1 | |
| SCHEMBL8782195 | 0.75 | MRGPRX4 (0.72) | MRGPRX4ADRB2TDP1NPC1RAB9A | |
| SCHEMBL11512939 | 0.75 | MRGPRX4 (0.69) | MRGPRX4MAPTHPGDSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4059615-A | INSECTICIDE, POLYMER INTERMEDIATE | HOOKER CHEMICALS & PLASTICS CORPORATION (US) | 1977-11-22 | — | — | US | disclosed |