Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 1/20 | 0.57 |
| ▸ | FABP4 | P15090 | 1/20 | 0.57 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.57 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4600472 | 0.85 | FABP3 (0.55) | FABP3FABP4FABP5IDO1HDAC8 | |
| SCHEMBL3920119 | 0.83 | MAPT (0.59) | FABP4FABP5IDO1HDAC8MAPT | |
| SCHEMBL11711706 | 0.81 | MRGPRX4 (0.65) | MRGPRX4MAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL12301132 | 0.81 | PTGER1 (0.54) | FABP3FABP4FABP5IDO1HDAC8 | |
| SCHEMBL2557709 | 0.80 | ENPP2 (0.63) | FABP3FABP4FABP5IDO1HDAC8 | |
| SCHEMBL5839484 | 0.79 | FABP3 (0.78) | FABP3FABP4FABP5HDAC8MRGPRX4 | |
| SCHEMBL9825372 | 0.78 | FABP3 (0.57) | FABP3FABP4FABP5IDO1HDAC8 | |
| SCHEMBL9414542 | 0.78 | FABP4 (0.51) | FABP3FABP4FABP5IDO1HDAC8 | |
| SCHEMBL9824901 | 0.78 | FABP3 (0.64) | FABP3FABP4FABP5HDAC8MRGPRX4 | |
| SCHEMBL8371564 | 0.77 | POLB (0.54) | FABP3FABP4FABP5IDO1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4029955-A | — | — | None | — | — | JP | disclosed |
| JP-H0429955-A | HALOGEN-SUBSTITUTED HYDROXYPHENYL BENZYL ETHERS | WAKAYAMA PREF GOV | 1992-01-31 | — | — | JP | disclosed |
| US-4563526-A | PROSTAGLANDIN-SYNTHETASE INHIBITORS | FORSYTH DENTAL INFIRMARY FOR CHILDREN (US) | 1986-01-07 | — | — | US | disclosed |
| US-RE31624-E | INHIBITORS OF PROSTAGLANDIN SYNTHESIS | FORSYTH DENTAL INFIRMARY FOR CHILDREN (US) | 1984-07-03 | — | — | US | disclosed |
| US-4244956-A | PROSTAGLANDIN SYNTHESIS INHIBITORS | FORSYTH DENTAL INFIRMARY FOR CHILDREN (US) | 1981-01-13 | — | — | US | disclosed |